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MYOCARDITIS
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Tschope, Carsten


Publications

Impact Factor

Cites


ReferenceImpact FactorCitesQuartile
Thurner L, Kessel C, Fadle N, Regitz E, Seidel F, Kindermann I, Lohse S, Kos I, Tschope C, Kheiroddin P, Kiblboeck D, Hoffmann MC, Bette B, Carbon G, Cetin O, Preuss KD, Christofyllakis K, Bittenbring JT, Pickardt T, Fischer Y, Thiele H, Baldus S, Stangl K, Steiner S, Gietzen F, Kerber S, Deneke T, Jellinghaus S, Linke A, Ibrahim K, Grabmaier U, Massberg S, Thilo C, Greulich S, Gawaz M, Mayatepek E, Meyer-Dobkowitz L, Kindermann M, Birk E, Birk M, Lainscak M, Foell D, Lepper PM, Bals R, Krawczyk M, Mevorach D, Hasin T, Keren A, Kabesch M, Abdul-Khaliq H, Smola S, Bewarder M, Thurner B, Bohm M, Pfeifer J, Klingel K. IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination. N Engl J Med. 2022 Oct 20;387(16):1524-1527. doi: 10.1056/NEJMc2205667. Epub 2022 Sep 21. No abstract available. PubMed PMID: 36130012; PubMed Central PMCID: PMC9513854.
176.079
Tschope C, Ammirati E, Bozkurt B, Caforio ALP, Cooper LT, Felix SB, Hare JM, Heidecker B, Heymans S, Hubner N, Kelle S, Klingel K, Maatz H, Parwani AS, Spillmann F, Starling RC, Tsutsui H, Seferovic P, Van Linthout S. Myocarditis and inflammatory cardiomyopathy: current evidence and future directions. Nat Rev Cardiol. 2021 Mar;18(3):169-193. doi: 10.1038/s41569-020-00435-x. Epub 2020 Oct 12. PubMed PMID: 33046850; PubMed Central PMCID: PMC7548534.
49.421
Holzmann M, Nicko A, Kuhl U, Noutsias M, Poller W, Hoffmann W, Morguet A, Witzenbichler B, Tschope C, Schultheiss HP, Pauschinger M. Complication rate of right ventricular endomyocardial biopsy via the femoral approach: a retrospective and prospective study analyzing 3048 diagnostic procedures over an 11-year period. Circulation. 2008 Oct 21;118(17):1722-8. doi: 10.1161/CIRCULATIONAHA.107.743427. Epub 2008 Oct 6. PubMed PMID: 18838566.
39.918
Rahnefeld A, Klingel K, Schuermann A, Diny NL, Althof N, Lindner A, Bleienheuft P, Savvatis K, Respondek D, Opitz E, Ketscher L, Sauter M, Seifert U, Tschope C, Poller W, Knobeloch KP, Voigt A. Ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) in host defense against heart failure in a mouse model of virus-induced cardiomyopathy. Circulation. 2014 Oct 28;130(18):1589-600. doi: 10.1161/CIRCULATIONAHA.114.009847. Epub 2014 Aug 27. PubMed PMID: 25165091.
39.918
Pinkert S, Westermann D, Wang X, Klingel K, Dorner A, Savvatis K, Grossl T, Krohn S, Tschope C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H. Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor. Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23. PubMed PMID: 19933937.
39.918
Westermann D, Savvatis K, Lindner D, Zietsch C, Becher PM, Hammer E, Heimesaat MM, Bereswill S, Volker U, Escher F, Riad A, Plendl J, Klingel K, Poller W, Schultheiss HP, Tschope C. Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation. 2011 Nov 8;124(19):2082-93. doi: 10.1161/CIRCULATIONAHA.111.035964. Epub 2011 Oct 10. PubMed PMID: 21986287.
39.918
Spillmann F, Van Linthout S, Schmidt G, Klein O, Hamdani N, Mairinger T, Krackhardt F, Maroski B, Schlabs T, Soltani S, Anker S, Potapov EV, Burkhoff D, Pieske B, Tschope C. Mode-of-action of the PROPELLA concept in fulminant myocarditis. Eur Heart J. 2019 Jul 1;40(26):2164-2169. doi: 10.1093/eurheartj/ehz124. PubMed PMID: 30891599; PubMed Central PMCID: PMC6612367.
35.855
Shi Y, Chen C, Lisewski U, Wrackmeyer U, Radke M, Westermann D, Sauter M, Tschope C, Poller W, Klingel K, Gotthardt M. Cardiac deletion of the Coxsackievirus-adenovirus receptor abolishes Coxsackievirus B3 infection and prevents myocarditis in vivo. J Am Coll Cardiol. 2009 Apr 7;53(14):1219-26. doi: 10.1016/j.jacc.2008.10.064. PubMed PMID: 19341864.
27.203
Weithauser A, Bobbert P, Antoniak S, Bohm A, Rauch BH, Klingel K, Savvatis K, Kroemer HK, Tschope C, Stroux A, Zeichhardt H, Poller W, Mackman N, Schultheiss HP, Rauch U. Protease-activated receptor-2 regulates the innate immune response to viral infection in a coxsackievirus B3-induced myocarditis. J Am Coll Cardiol. 2013 Nov 5;62(19):1737-45. doi: 10.1016/j.jacc.2013.05.076. Epub 2013 Jul 17. PubMed PMID: 23871888; PubMed Central PMCID: PMC4077621.
27.203
Tschope C, Cooper LT, Torre-Amione G, Van Linthout S. Management of Myocarditis-Related Cardiomyopathy in Adults. Circ Res. 2019 May 24;124(11):1568-1583. doi: 10.1161/CIRCRESAHA.118.313578. PubMed PMID: 31120823.
23.213
Noutsias M, Tschope C. Giant cell myocarditis: still a conundrum. The need for a worldwide registry. Eur J Heart Fail. 2016 Dec;18(12):1459-1461. doi: 10.1002/ejhf.648. Epub 2016 Sep 19. No abstract available. PubMed PMID: 27647798.
17.349
de Boer RA, De Keulenaer G, Bauersachs J, Brutsaert D, Cleland JG, Diez J, Du XJ, Ford P, Heinzel FR, Lipson KE, McDonagh T, Lopez-Andres N, Lunde IG, Lyon AR, Pollesello P, Prasad SK, Tocchetti CG, Mayr M, Sluijter JPG, Thum T, Tschope C, Zannad F, Zimmermann WH, Ruschitzka F, Filippatos G, Lindsey ML, Maack C, Heymans S. Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology. Eur J Heart Fail. 2019 Mar;21(3):272-285. doi: 10.1002/ejhf.1406. Epub 2019 Feb 4. PubMed PMID: 30714667; PubMed Central PMCID: PMC6607480.
17.349
Van Linthout S, Klingel K, Tschope C. SARS-CoV-2-related myocarditis-like syndromes Shakespeare's question: what's in a name? Eur J Heart Fail. 2020 Jun;22(6):922-925. doi: 10.1002/ejhf.1899. Epub 2020 Jun 20. No abstract available. PubMed PMID: 32430971; PubMed Central PMCID: PMC7276849.
17.349
Seferovic PM, Tsutsui H, McNamara DM, Ristic AD, Basso C, Bozkurt B, Cooper LT Jr, Filippatos G, Ide T, Inomata T, Klingel K, Linhart A, Lyon AR, Mehra MR, Polovina M, Milinkovic I, Nakamura K, Anker SD, Veljic I, Ohtani T, Okumura T, Thum T, Tschope C, Rosano G, Coats AJS, Starling RC. Heart Failure Association of the ESC, Heart Failure Society of America and Japanese Heart Failure Society Position statement on endomyocardial biopsy. Eur J Heart Fail. 2021 Jun;23(6):854-871. doi: 10.1002/ejhf.2190. Epub 2021 May 19. Erratum In: Eur J Heart Fail. 2022 Apr;24(4):732. PubMed PMID: 34010472.
17.349
Pauschinger M, Rutschow S, Chandrasekharan K, Westermann D, Weitz A, Peter Schwimmbeck L, Zeichhardt H, Poller W, Noutsias M, Li J, Schultheiss HP, Tschope C. Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response. Eur J Heart Fail. 2005 Jun;7(4):444-52. doi: 10.1016/j.ejheart.2004.07.002. PubMed PMID: 15921778.
17.349
Heidecker B, Dagan N, Balicer R, Eriksson U, Rosano G, Coats A, Tschope C, Kelle S, Poland GA, Frustaci A, Klingel K, Martin P, Hare JM, Cooper LT, Pantazis A, Imazio M, Prasad S, Luscher TF. Myocarditis following COVID-19 vaccine: incidence, presentation, diagnosis, pathophysiology, therapy, and outcomes put into perspective. A clinical consensus document supported by the Heart Failure Association of the European Society of Cardiology (ESC) and the ESC Working Group on Myocardial and Pericardial Diseases. Eur J Heart Fail. 2022 Nov;24(11):2000-2018. doi: 10.1002/ejhf.2669. Epub 2022 Oct 6. PubMed PMID: 36065751; PubMed Central PMCID: PMC9538893.
17.349
Pinkert S, Pryshliak M, Pappritz K, Knoch K, Hazini A, Dieringer B, Schaar K, Dong F, Hinze L, Lin J, Lassner D, Klopfleisch R, Solimena M, Tschope C, Kaya Z, El-Shafeey M, Beling A, Kurreck J, Van Linthout S, Klingel K, Fechner H. Development of a new mouse model for coxsackievirus-induced myocarditis by attenuating coxsackievirus B3 virulence in the pancreas. Cardiovasc Res. 2020 Aug 1;116(10):1756-1766. doi: 10.1093/cvr/cvz259. PubMed PMID: 31598635.
13.081
Li J, Schwimmbeck PL, Tschope C, Leschka S, Husmann L, Rutschow S, Reichenbach F, Noutsias M, Kobalz U, Poller W, Spillmann F, Zeichhardt H, Schultheiss HP, Pauschinger M. Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction. Cardiovasc Res. 2002 Nov;56(2):235-47. doi: 10.1016/s0008-6363(02)00546-1. PubMed PMID: 12393094.
13.081
Gyongyosi M, Alcaide P, Asselbergs FW, Brundel BJJM, Camici GG, da Costa Martins P, Ferdinandy P, Fontana M, Girao H, Gnecchi M, Gollmann-Tepekoylu C, Kleinbongard P, Krieg T, Madonna R, Paillard M, Pantazis A, Perrino C, Pesce M, Schiattarella GG, Sluijter JPG, Steffens S, Tschope C, Van Linthout S, Davidson SM. Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: A joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases. Cardiovasc Res. 2022 Jul 25:cvac115. doi: 10.1093/cvr/cvac115. Online ahead of print. PubMed PMID: 35875883; PubMed Central PMCID: PMC9384470.
13.081
Savvatis K, Muller I, Frohlich M, Pappritz K, Zietsch C, Hamdani N, Grote K, Schieffer B, Klingel K, Van Linthout S, Linke WA, Schultheiss HP, Tschope C. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis. Basic Res Cardiol. 2014;109(6):449. doi: 10.1007/s00395-014-0449-2. Epub 2014 Oct 25. PubMed PMID: 25344085.
12.416
Kraft L, Erdenesukh T, Sauter M, Tschope C, Klingel K. Blocking the IL-1beta signalling pathway prevents chronic viral myocarditis and cardiac remodeling. Basic Res Cardiol. 2019 Jan 23;114(2):11. doi: 10.1007/s00395-019-0719-0. PubMed PMID: 30673858.
12.416
Muller I, Vogl T, Pappritz K, Miteva K, Savvatis K, Rohde D, Most P, Lassner D, Pieske B, Kuhl U, Van Linthout S, Tschope C. Pathogenic Role of the Damage-Associated Molecular Patterns S100A8 and S100A9 in Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 2017 Nov;10(11):e004125. doi: 10.1161/CIRCHEARTFAILURE.117.004125. PubMed PMID: 29158436.
10.447
Pinkert S, Dieringer B, Klopfleisch R, Savvatis K, Van Linthout S, Pryshliak M, Tschope C, Klingel K, Kurreck J, Beling A, Fechner H. Early Treatment of Coxsackievirus B3-Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy. Circ Heart Fail. 2019 Nov;12(11):e005250. doi: 10.1161/CIRCHEARTFAILURE.119.005250. Epub 2019 Nov 13. PubMed PMID: 31718319.
10.447
Tschope C, Muller I, Xia Y, Savvatis K, Pappritz K, Pinkert S, Lassner D, Heimesaat MM, Spillmann F, Miteva K, Bereswill S, Schultheiss HP, Fechner H, Pieske B, Kuhl U, Van Linthout S. NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 2017 Sep;10(9):e003870. doi: 10.1161/CIRCHEARTFAILURE.117.003870. PubMed PMID: 28912259.
10.447
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschope C, Cooper LT Jr, Camici PG. Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document. Circ Heart Fail. 2020 Nov;13(11):e007405. doi: 10.1161/CIRCHEARTFAILURE.120.007405. Epub 2020 Nov 12. PubMed PMID: 33176455; PubMed Central PMCID: PMC7673642.
10.447
Halle M, Binzenhofer L, Mahrholdt H, Johannes Schindler M, Esefeld K, Tschope C. Myocarditis in athletes: A clinical perspective. Eur J Prev Cardiol. 2020 Apr 17:2047487320909670. doi: 10.1177/2047487320909670. Online ahead of print. PubMed PMID: 33611403.
8.526
Stein EA, Pinkert S, Becher PM, Geisler A, Zeichhardt H, Klopfleisch R, Poller W, Tschope C, Lassner D, Fechner H, Kurreck J. Combination of RNA interference and virus receptor trap exerts additive antiviral activity in coxsackievirus B3-induced myocarditis in mice. J Infect Dis. 2015 Feb 15;211(4):613-22. doi: 10.1093/infdis/jiu504. Epub 2014 Sep 5. PubMed PMID: 25193982.
7.759
Miteva K, Pappritz K, El-Shafeey M, Dong F, Ringe J, Tschope C, Van Linthout S. Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis. Stem Cells Transl Med. 2017 Apr;6(4):1249-1261. doi: 10.1002/sctm.16-0353. Epub 2017 Jan 3. PubMed PMID: 28186704; PubMed Central PMCID: PMC5442851.
7.655
Escher F, Westermann D, Gaub R, Pronk J, Bock T, Al-Saadi N, Kuhl U, Schultheiss HP, Tschope C. Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis. Heart. 2011 May;97(9):709-14. doi: 10.1136/hrt.2010.199489. Epub 2010 Dec 5. PubMed PMID: 21134904.
7.365
Seferovic PM, Tsutsui H, Mcnamara DM, Ristic AD, Basso C, Bozkurt B, Cooper LT, Filippatos G, Ide T, Inomata T, Klingel K, Linhart A, Lyon AR, Mehra MR, Polovina M, Milinkovic I, Nakamura K, Anker SD, Veljic I, Ohtani T, Okumura T, Thum T, Tschope C, Rosano G, Coats AJS, Starling RC. Heart Failure Association, Heart Failure Society of America, and Japanese Heart Failure Society Position Statement on Endomyocardial Biopsy. J Card Fail. 2021 Jul;27(7):727-743. doi: 10.1016/j.cardfail.2021.04.010. Epub 2021 May 19. PubMed PMID: 34022400.
6.592
Escher F, Kuhl U, Lassner D, Poller W, Westermann D, Pieske B, Tschope C, Schultheiss HP. Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy. Clin Res Cardiol. 2016 Dec;105(12):1011-1020. doi: 10.1007/s00392-016-1011-z. Epub 2016 Jun 16. PubMed PMID: 27312326.
6.138
Coronado MJ, Bruno KA, Blauwet LA, Tschope C, Cunningham MW, Pankuweit S, van Linthout S, Jeon ES, McNamara DM, Krejci J, Bienertova-Vasku J, Douglass EJ, Abston ED, Bucek A, Frisancho JA, Greenaway MS, Hill AR, Schultheiss HP, Cooper LT Jr, Fairweather D. Elevated Sera sST2 Is Associated With Heart Failure in Men </=50 Years Old With Myocarditis. J Am Heart Assoc. 2019 Jan 22;8(2):e008968. doi: 10.1161/JAHA.118.008968. PubMed PMID: 30638108; PubMed Central PMCID: PMC6497352.
6.106
Tanacli R, Doeblin P, Gotze C, Zieschang V, Faragli A, Stehning C, Korosoglou G, Erley J, Weiss J, Berger A, Propper F, Steinbeis F, Kuhne T, Seidel F, Geisel D, Cannon Walter-Rittel T, Stawowy P, Witzenrath M, Klingel K, Van Linthout S, Pieske B, Tschope C, Kelle S. COVID-19 vs. Classical Myocarditis Associated Myocardial Injury Evaluated by Cardiac Magnetic Resonance and Endomyocardial Biopsy. Front Cardiovasc Med. 2021 Dec 24;8:737257. doi: 10.3389/fcvm.2021.737257. eCollection 2021. PubMed PMID: 35004872; PubMed Central PMCID: PMC8739473.
5.846
Tschope C, Spillmann F, Potapov E, Faragli A, Rapis K, Nelki V, Post H, Schmidt G, Alogna A. The "TIDE"-Algorithm for the Weaning of Patients With Cardiogenic Shock and Temporarily Mechanical Left Ventricular Support With Impella Devices. A Cardiovascular Physiology-Based Approach. Front Cardiovasc Med. 2021 Feb 19;8:563484. doi: 10.3389/fcvm.2021.563484. eCollection 2021. PubMed PMID: 33681302; PubMed Central PMCID: PMC7933542.
5.846
Tschope C, Alogna A, Faragli A, Klingel K, Schmidt G, Heilmann TW, B Bastos M, Spillmann F. Case Report First-in-Man Method Description: Left Ventricular Unloading With iVAC2L During Veno-Arterial Extracorporeal Membrane Oxygenation: From Veno-Arterial Extracorporeal Membrane Oxygenation to ECMELLA to EC-iVAC(R). Front Cardiovasc Med. 2020 Sep 25;7:563448. doi: 10.3389/fcvm.2020.563448. eCollection 2020. PubMed PMID: 33102536; PubMed Central PMCID: PMC7545402.
5.846
Pappritz K, Savvatis K, Miteva K, Kerim B, Dong F, Fechner H, Muller I, Brandt C, Lopez B, Gonzalez A, Ravassa S, Klingel K, Diez J, Reinke P, Volk HD, Van Linthout S, Tschope C. Immunomodulation by adoptive regulatory T-cell transfer improves Coxsackievirus B3-induced myocarditis. FASEB J. 2018 Jun 4:fj201701408R. doi: 10.1096/fj.201701408R. Online ahead of print. PubMed PMID: 29863913.
5.834
Muller I, Janson L, Sauter M, Pappritz K, Linthout SV, Tschope C, Klingel K. Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis. Viruses. 2021 May 12;13(5):889. doi: 10.3390/v13050889. PubMed PMID: 34065891; PubMed Central PMCID: PMC8151145.
5.818
Elsanhoury A, Kuhl U, Stautner B, Klein O, Krannich A, Morris D, Willner M, Jankowska E, Klingel K, Van Linthout S, Tschope C. The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention. Viruses. 2022 Jan 31;14(2):299. doi: 10.3390/v14020299. PubMed PMID: 35215893; PubMed Central PMCID: PMC8879301.
5.818
Carai P, Papageorgiou AP, Van Linthout S, Deckx S, Velthuis S, Lutgens E, Wijnands E, Tschope C, Schmuttermaier C, Kzhyshkowska J, Jones EAV, Heymans S. Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. J Mol Cell Cardiol. 2022 Apr;165:31-39. doi: 10.1016/j.yjmcc.2021.12.009. Epub 2021 Dec 28. PubMed PMID: 34968453.
5.763
Antoniak S, Boltzen U, Riad A, Kallwellis-Opara A, Rohde M, Dorner A, Tschope C, Noutsias M, Pauschinger M, Schultheiss HP, Rauch U. Viral myocarditis and coagulopathy: increased tissue factor expression and plasma thrombogenicity. J Mol Cell Cardiol. 2008 Jul;45(1):118-26. doi: 10.1016/j.yjmcc.2008.03.013. Epub 2008 Mar 29. PubMed PMID: 18495150.
5.763
Westermann D, Savvatis K, Schultheiss HP, Tschope C. Immunomodulation and matrix metalloproteinases in viral myocarditis. J Mol Cell Cardiol. 2010 Mar;48(3):468-73. doi: 10.1016/j.yjmcc.2009.08.019. Epub 2009 Sep 1. PubMed PMID: 19729021.
5.763
Riad A, Westermann D, Zietsch C, Savvatis K, Becher PM, Bereswill S, Heimesaat MM, Lettau O, Lassner D, Dorner A, Poller W, Busch M, Felix SB, Schultheiss HP, Tschope C. TRIF is a critical survival factor in viral cardiomyopathy. J Immunol. 2011 Feb 15;186(4):2561-70. doi: 10.4049/jimmunol.1002029. Epub 2011 Jan 14. PubMed PMID: 21239721.
5.426
Li J, Leschka S, Rutschow S, Schwimmbeck PL, Husmann L, Noutsias M, Westermann D, Poller W, Zeichhardt H, Klingel K, Tschope C, Schultheiss HP, Pauschinger M. Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis. Eur J Pharmacol. 2007 Jan 5;554(1):60-8. doi: 10.1016/j.ejphar.2006.08.024. Epub 2006 Aug 26. PubMed PMID: 17113076.
5.195
Rutschow S, Leschka S, Westermann D, Puhl K, Weitz A, Ladyszenskij L, Jaeger S, Zeichhardt H, Noutsias M, Schultheiss HP, Tschope C, Pauschinger M. Left ventricular enlargement in coxsackievirus-B3 induced chronic myocarditis--ongoing inflammation and an imbalance of the matrix degrading system. Eur J Pharmacol. 2010 Mar 25;630(1-3):145-51. doi: 10.1016/j.ejphar.2009.12.019. Epub 2009 Dec 24. PubMed PMID: 20035743.
5.195
Tschope C, Westermann D, Steendijk P, Noutsias M, Rutschow S, Weitz A, Schwimmbeck PL, Schultheiss HP, Pauschinger M. Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol. Eur J Pharmacol. 2004 May 3;491(2-3):173-9. doi: 10.1016/j.ejphar.2004.03.032. PubMed PMID: 15140634.
5.195
Miteva K, Van Linthout S, Volk HD, Tschope C. Immunomodulatory effects of mesenchymal stromal cells revisited in the context of inflammatory cardiomyopathy. Stem Cells Int. 2013;2013:353097. doi: 10.1155/2013/353097. Epub 2013 Jun 19. PubMed PMID: 23853610; PubMed Central PMCID: PMC3703801.
5.131
Riad A, Westermann D, Escher F, Becher PM, Savvatis K, Lettau O, Heimesaat MM, Bereswill S, Volk HD, Schultheiss HP, Tschope C. Myeloid differentiation factor-88 contributes to TLR9-mediated modulation of acute coxsackievirus B3-induced myocarditis in vivo. Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2024-31. doi: 10.1152/ajpheart.01188.2009. Epub 2010 Mar 12. PubMed PMID: 20228254.
5.125
Miteva K, Pappritz K, Sosnowski M, El-Shafeey M, Muller I, Dong F, Savvatis K, Ringe J, Tschope C, Van Linthout S. Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy. Sci Rep. 2018 Feb 12;8(1):2820. doi: 10.1038/s41598-018-20686-6. PubMed PMID: 29434214; PubMed Central PMCID: PMC5809634.
4.996
Westphal JG, Rigopoulos AG, Bakogiannis C, Ludwig SE, Mavrogeni S, Bigalke B, Doenst T, Pauschinger M, Tschope C, Schulze PC, Noutsias M. The MOGE(S) classification for cardiomyopathies: current status and future outlook. Heart Fail Rev. 2017 Nov;22(6):743-752. doi: 10.1007/s10741-017-9641-4. PubMed PMID: 28721466.
4.654
Katzmann JL, Schlattmann P, Rigopoulos AG, Noutsias E, Bigalke B, Pauschinger M, Tschope C, Sedding D, Schulze PC, Noutsias M. Meta-analysis on the immunohistological detection of inflammatory cardiomyopathy in endomyocardial biopsies. Heart Fail Rev. 2020 Mar;25(2):277-294. doi: 10.1007/s10741-019-09835-9. PubMed PMID: 31396762.
4.654
Lindner D, Li J, Savvatis K, Klingel K, Blankenberg S, Tschope C, Westermann D. Cardiac fibroblasts aggravate viral myocarditis: cell specific coxsackievirus B3 replication. Mediators Inflamm. 2014;2014:519528. doi: 10.1155/2014/519528. Epub 2014 Oct 13. PubMed PMID: 25374444; PubMed Central PMCID: PMC4211177.
4.529
Escher F, Kasner M, Kuhl U, Heymer J, Wilkenshoff U, Tschope C, Schultheiss HP. New echocardiographic findings correlate with intramyocardial inflammation in endomyocardial biopsies of patients with acute myocarditis and inflammatory cardiomyopathy. Mediators Inflamm. 2013;2013:875420. doi: 10.1155/2013/875420. Epub 2013 Mar 20. PubMed PMID: 23576857; PubMed Central PMCID: PMC3616345.
4.529
Tschope C, Nelki V, Trippel TD, Klingel K, Abawi D, Alogna A. Safety and usefulness of left ventricular endomyocardial biopsy in new- onset acute heart failure requiring mechanical support by an Impella(R) device. Int J Cardiol. 2022 Dec 1;368:49-52. doi: 10.1016/j.ijcard.2022.08.010. Epub 2022 Aug 6. PubMed PMID: 35944774.
4.039
Veronese G, Ammirati E, Chen C, Klingel K, Suzuki M, Okumura T, Maisch B, Zuo H, Ni L, Jiang J, Zhang J, Wang H, Zhou N, Tschope C, Cooper LT, Wang DW. Management perspectives from the 2019 Wuhan international workshop on fulminant myocarditis. Int J Cardiol. 2021 Feb 1;324:131-138. doi: 10.1016/j.ijcard.2020.10.063. Epub 2020 Oct 26. PubMed PMID: 33122017.
4.039
Kasner M, Sinning D, Escher F, Lassner D, Kuhl U, Schultheiss HP, Tschope C. The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy. Int J Cardiol. 2013 Oct 3;168(3):3023-4. doi: 10.1016/j.ijcard.2013.04.016. Epub 2013 May 20. No abstract available. PubMed PMID: 23701925.
4.039
Kasner M, Aleksandrov A, Escher F, Al-Saadi N, Makowski M, Spillmann F, Genger M, Schultheiss HP, Kuhl U, Pieske B, Morris DA, Noutsias M, Tschope C. Multimodality imaging approach in the diagnosis of chronic myocarditis with preserved left ventricular ejection fraction (MCpEF): The role of 2D speckle-tracking echocardiography. Int J Cardiol. 2017 Sep 15;243:374-378. doi: 10.1016/j.ijcard.2017.05.038. Epub 2017 May 16. PubMed PMID: 28536004.
4.039
Miteva K, Haag M, Peng J, Savvatis K, Becher PM, Seifert M, Warstat K, Westermann D, Ringe J, Sittinger M, Schultheiss HP, Tschope C, Van Linthout S. Human cardiac-derived adherent proliferating cells reduce murine acute Coxsackievirus B3-induced myocarditis. PLoS One. 2011;6(12):e28513. doi: 10.1371/journal.pone.0028513. Epub 2011 Dec 9. PubMed PMID: 22174827; PubMed Central PMCID: PMC3235117.
3.752
Muller I, Pappritz K, Savvatis K, Puhl K, Dong F, El-Shafeey M, Hamdani N, Hamann I, Noutsias M, Infante-Duarte C, Linke WA, Van Linthout S, Tschope C. CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis. PLoS One. 2017 Aug 11;12(8):e0182643. doi: 10.1371/journal.pone.0182643. eCollection 2017. PubMed PMID: 28800592; PubMed Central PMCID: PMC5553786.
3.752
Savvatis K, van Linthout S, Miteva K, Pappritz K, Westermann D, Schefold JC, Fusch G, Weithauser A, Rauch U, Becher PM, Klingel K, Ringe J, Kurtz A, Schultheiss HP, Tschope C. Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis. PLoS One. 2012;7(7):e41047. doi: 10.1371/journal.pone.0041047. Epub 2012 Jul 17. PubMed PMID: 22815907; PubMed Central PMCID: PMC3398879.
3.752
Tscholl V, Wielander D, Kelch F, Stroux A, Attanasio P, Tschope C, Landmesser U, Roser M, Huemer M, Heidecker B, Nagel P. Benefit of a wearable cardioverter defibrillator for detection and therapy of arrhythmias in patients with myocarditis. ESC Heart Fail. 2021 Aug;8(4):2428-2437. doi: 10.1002/ehf2.13353. Epub 2021 Apr 22. PubMed PMID: 33887109; PubMed Central PMCID: PMC8318510.
3.612
Pappritz K, Lin J, El-Shafeey M, Fechner H, Kuhl U, Alogna A, Spillmann F, Elsanhoury A, Schulz R, Tschope C, Van Linthout S. Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis. ESC Heart Fail. 2022 Apr;9(2):925-941. doi: 10.1002/ehf2.13845. Epub 2022 Feb 17. PubMed PMID: 35178861; PubMed Central PMCID: PMC8934990.
3.612
Spillmann F, Kuhl U, Van Linthout S, Dominguez F, Escher F, Schultheiss HP, Pieske B, Tschope C. Reversible transition from a hypertrophic to a dilated cardiomyopathy. ESC Heart Fail. 2016 Jun;3(2):138-142. doi: 10.1002/ehf2.12072. Epub 2015 Dec 9. PubMed PMID: 27774273; PubMed Central PMCID: PMC5064744.
3.612
Tschope C, Sherif M, Anker MS, Geisel D, Kuehne T, Kelle S. COVID-19-convalescence phase unmasks a silent myocardial infarction due to coronary plaque rupture. ESC Heart Fail. 2021 Apr;8(2):971-973. doi: 10.1002/ehf2.13186. Epub 2021 Jan 6. PubMed PMID: 33410259; PubMed Central PMCID: PMC8006695.
3.612
Ferrero P, Piazza I, Kuhl U, Grosu A, Tschope C, Senni M. QRS fragmentation as a possible electrocardiographic diagnostic marker in patients with acute myocarditis: preliminary histopathological validation. ESC Heart Fail. 2020 Oct;7(5):2527-2533. doi: 10.1002/ehf2.12821. Epub 2020 Jun 19. PubMed PMID: 32562382; PubMed Central PMCID: PMC7524046.
3.612
Tschope C, Van Linthout S, Jager S, Arndt R, Trippel T, Muller I, Elsanhoury A, Rutschow S, Anker SD, Schultheiss HP, Pauschinger M, Spillmann F, Pappritz K. Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis. ESC Heart Fail. 2020 Oct;7(5):2838-2852. doi: 10.1002/ehf2.12887. Epub 2020 Jul 14. PubMed PMID: 32662949; PubMed Central PMCID: PMC7405199.
3.612
Blaschke F, Lacour P, Dang PL, Parwani AS, Hohendanner F, Walter T, Klingel K, Kuhl U, Heinzel FR, Sherif M, Boldt LH, Pieske B, Tschope C. Wearable cardioverter-defibrillator: friend or foe in suspected myocarditis? ESC Heart Fail. 2021 Aug;8(4):2591-2596. doi: 10.1002/ehf2.13340. Epub 2021 May 1. PubMed PMID: 33932118; PubMed Central PMCID: PMC8318471.
3.612
Muller I, Vogl T, Kuhl U, Krannich A, Banks A, Trippel T, Noutsias M, Maisel AS, van Linthout S, Tschope C. Serum alarmin S100A8/S100A9 levels and its potential role as biomarker in myocarditis. ESC Heart Fail. 2020 Aug;7(4):1442-1451. doi: 10.1002/ehf2.12760. Epub 2020 May 28. PubMed PMID: 32462801; PubMed Central PMCID: PMC7373886.
3.612
Van Linthout S, Elsanhoury A, Klein O, Sosnowski M, Miteva K, Lassner D, Abou-El-Enein M, Pieske B, Kuhl U, Tschope C. Telbivudine in chronic lymphocytic myocarditis and human parvovirus B19 transcriptional activity. ESC Heart Fail. 2018 Oct;5(5):818-829. doi: 10.1002/ehf2.12341. Epub 2018 Aug 11. PubMed PMID: 30099854; PubMed Central PMCID: PMC6165949.
3.612
Malz R, Weithauser A, Tschope C, Schultheiss HP, Rauch U. Inhibition of coagulation factor Xa improves myocardial function during CVB3-induced myocarditis. Cardiovasc Ther. 2014 Jun;32(3):113-9. doi: 10.1111/1755-5922.12069. PubMed PMID: 24533719.
3.368
Tschope C, Van Linthout S, Klein O, Mairinger T, Krackhardt F, Potapov EV, Schmidt G, Burkhoff D, Pieske B, Spillmann F. Mechanical Unloading by Fulminant Myocarditis: LV-IMPELLA, ECMELLA, BI-PELLA, and PROPELLA Concepts. J Cardiovasc Transl Res. 2019 Apr;12(2):116-123. doi: 10.1007/s12265-018-9820-2. Epub 2018 Aug 6. PubMed PMID: 30084076; PubMed Central PMCID: PMC6497621.
3.216
Elsanhoury A, Tschope C, Van Linthout S. A Toolbox of Potential Immune-Related Therapies for Inflammatory Cardiomyopathy. J Cardiovasc Transl Res. 2021 Feb;14(1):75-87. doi: 10.1007/s12265-020-10025-4. Epub 2020 May 21. PubMed PMID: 32440911; PubMed Central PMCID: PMC7892499.
3.216
Van Linthout S, Tschope C. Viral myocarditis: a prime example for endomyocardial biopsy-guided diagnosis and therapy. Curr Opin Cardiol. 2018 May;33(3):325-333. doi: 10.1097/HCO.0000000000000515. PubMed PMID: 29528906; PubMed Central PMCID: PMC5908263.
2.108
Lindner D, Hilbrandt M, Marggraf K, Becher PM, Hilfiker-Kleiner D, Klingel K, Pauschinger M, Schultheiss HP, Tschope C, Westermann D. Protective Function of STAT3 in CVB3-Induced Myocarditis. Cardiol Res Pract. 2012;2012:437623. doi: 10.1155/2012/437623. Epub 2012 May 24. PubMed PMID: 22675647; PubMed Central PMCID: PMC3366200.
1.99
Nersesian G, Tschope C, Spillmann F, Gromann T, Roehrich L, Mueller M, Mulzer J, Starck C, Falk V, Schoenrath F, Potapov E. Prediction of survival of patients in cardiogenic shock treated by surgically implanted Impella 5+ short-term left ventricular assist device. Interact Cardiovasc Thorac Surg. 2020 Oct 1;31(4):475-482. doi: 10.1093/icvts/ivaa150. PubMed PMID: 32879947.
1.978
Tschope C, Kuhl U. [Myocarditis and inflammatory cardiomyopathy--current treatment options]. Dtsch Med Wochenschr. 2016 Jan;141(2):95-102. doi: 10.1055/s-0041-107710. Epub 2016 Jan 22. German. PubMed PMID: 26800069.
0.653
Tschope C, Van Linthout S, Spillmann F, Posch MG, Reinke P, Volk HD, Elsanhoury A, Kuhl U. Targeting CD20+ B-lymphocytes in inflammatory dilated cardiomyopathy with rituximab improves clinical course: a case series. Eur Heart J Case Rep. 2019 Sep 1;3(3):ytz131. doi: 10.1093/ehjcr/ytz131. PubMed PMID: 31365055; PubMed Central PMCID: PMC6764574.
Dominguez F, Kuhl U, Pieske B, Garcia-Pavia P, Tschope C. Update on Myocarditis and Inflammatory Cardiomyopathy: Reemergence of Endomyocardial Biopsy. Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):178-87. doi: 10.1016/j.rec.2015.10.015. Epub 2016 Jan 12. PubMed PMID: 26795929.

Data Sources

PubMed
NCBI
SemanticScholar
Web of Science
Human Phenotype ontology
KEGG
IMIB-Arrixaca

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