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MYOCARDITIS
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Schultheiss, Heinz-Peter


Publications

Impact Factor

Cites


ReferenceImpact FactorCitesQuartile
Rother M, Krohn S, Kania G, Vanhoutte D, Eisenreich A, Wang X, Westermann D, Savvatis K, Dannemann N, Skurk C, Hilfiker-Kleiner D, Cathomen T, Fechner H, Rauch U, Schultheiss HP, Heymans S, Eriksson U, Scheibenbogen C, Poller W. Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator. Circulation. 2010 Dec 21;122(25):2688-98. doi: 10.1161/CIRCULATIONAHA.110.945261. Epub 2010 Dec 6. PubMed PMID: 21135363.
39.918
Kuhl U, Pauschinger M, Schwimmbeck PL, Seeberg B, Lober C, Noutsias M, Poller W, Schultheiss HP. Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction. Circulation. 2003 Jun 10;107(22):2793-8. doi: 10.1161/01.CIR.0000072766.67150.51. Epub 2003 May 27. PubMed PMID: 12771005.
39.918
Kuhl U, Pauschinger M, Bock T, Klingel K, Schwimmbeck CP, Seeberg B, Krautwurm L, Poller W, Schultheiss HP, Kandolf R. Parvovirus B19 infection mimicking acute myocardial infarction. Circulation. 2003 Aug 26;108(8):945-50. doi: 10.1161/01.CIR.0000085168.02782.2C. Epub 2003 Aug 18. PubMed PMID: 12925460.
39.918
Westermann D, Savvatis K, Lindner D, Zietsch C, Becher PM, Hammer E, Heimesaat MM, Bereswill S, Volker U, Escher F, Riad A, Plendl J, Klingel K, Poller W, Schultheiss HP, Tschope C. Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation. 2011 Nov 8;124(19):2082-93. doi: 10.1161/CIRCULATIONAHA.111.035964. Epub 2011 Oct 10. PubMed PMID: 21986287.
39.918
Noutsias M, Kuehl U, Lassner D, Gross U, Pauschinger M, Schultheiss HP, Gutberlet M. Images in cardiovascular medicine. Parvovirus-B19-associated active myocarditis with biventricular thrombi. Results of endomyocardial biopsy investigations and cardiac magnetic resonance imaging. Circulation. 2007 Apr 3;115(13):e378-80. doi: 10.1161/CIRCULATIONAHA.106.667360. No abstract available. PubMed PMID: 17404165.
39.918
Heymans S, Pauschinger M, De Palma A, Kallwellis-Opara A, Rutschow S, Swinnen M, Vanhoutte D, Gao F, Torpai R, Baker AH, Padalko E, Neyts J, Schultheiss HP, Van de Werf F, Carmeliet P, Pinto YM. Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis. Circulation. 2006 Aug 8;114(6):565-73. doi: 10.1161/CIRCULATIONAHA.105.591032. Epub 2006 Jul 31. PubMed PMID: 16880329.
39.918
Pinkert S, Westermann D, Wang X, Klingel K, Dorner A, Savvatis K, Grossl T, Krohn S, Tschope C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H. Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor. Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23. PubMed PMID: 19933937.
39.918
Holzmann M, Nicko A, Kuhl U, Noutsias M, Poller W, Hoffmann W, Morguet A, Witzenbichler B, Tschope C, Schultheiss HP, Pauschinger M. Complication rate of right ventricular endomyocardial biopsy via the femoral approach: a retrospective and prospective study analyzing 3048 diagnostic procedures over an 11-year period. Circulation. 2008 Oct 21;118(17):1722-8. doi: 10.1161/CIRCULATIONAHA.107.743427. Epub 2008 Oct 6. PubMed PMID: 18838566.
39.918
Kuhl U, Pauschinger M, Seeberg B, Lassner D, Noutsias M, Poller W, Schultheiss HP. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation. 2005 Sep 27;112(13):1965-70. doi: 10.1161/CIRCULATIONAHA.105.548156. Epub 2005 Sep 19. PubMed PMID: 16172268.
39.918
Kuhl U, Pauschinger M, Noutsias M, Seeberg B, Bock T, Lassner D, Poller W, Kandolf R, Schultheiss HP. High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation. 2005 Feb 22;111(7):887-93. doi: 10.1161/01.CIR.0000155616.07901.35. Epub 2005 Feb 7. PubMed PMID: 15699250.
39.918
Valaperti A, Nishii M, Liu Y, Naito K, Chan M, Zhang L, Skurk C, Schultheiss HP, Wells GA, Eriksson U, Liu PP. Innate immune interleukin-1 receptor-associated kinase 4 exacerbates viral myocarditis by reducing CCR5(+) CD11b(+) monocyte migration and impairing interferon production. Circulation. 2013 Oct 1;128(14):1542-54. doi: 10.1161/CIRCULATIONAHA.113.002275. Epub 2013 Sep 12. PubMed PMID: 24030499.
39.918
Schultheiss HP, Kuhl U, Cooper LT. The management of myocarditis. Eur Heart J. 2011 Nov;32(21):2616-25. doi: 10.1093/eurheartj/ehr165. Epub 2011 Jun 23. PubMed PMID: 21705357.
35.855
Loebel M, Holzhauser L, Hartwig JA, Shukla PC, Savvatis K, Jenke A, Gast M, Escher F, Becker SC, Bauer S, Stroux A, Beling A, Kespohl M, Pinkert S, Fechner H, Kuehl U, Lassner D, Poller W, Schultheiss HP, Zeller T, Blankenberg S, Papageorgiou AP, Heymans S, Landmesser U, Scheibenbogen C, Skurk C. The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis. Eur Heart J. 2018 Mar 7;39(10):876-887. doi: 10.1093/eurheartj/ehx624. PubMed PMID: 29136142.
35.855
Skurk C, Schultheiss HP. Mononuclear cell secretome in autoimmune myocarditis. Eur Heart J. 2015 Mar 14;36(11):650-2. doi: 10.1093/eurheartj/eht050. Epub 2013 Mar 19. No abstract available. PubMed PMID: 23513211.
35.855
Caforio AL, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, Fu M, Helio T, Heymans S, Jahns R, Klingel K, Linhart A, Maisch B, McKenna W, Mogensen J, Pinto YM, Ristic A, Schultheiss HP, Seggewiss H, Tavazzi L, Thiene G, Yilmaz A, Charron P, Elliott PM; European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi: 10.1093/eurheartj/eht210. Epub 2013 Jul 3. PubMed PMID: 23824828.
35.855
Gutberlet M, Spors B, Thoma T, Bertram H, Denecke T, Felix R, Noutsias M, Schultheiss HP, Kuhl U. Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence. Radiology. 2008 Feb;246(2):401-9. doi: 10.1148/radiol.2461062179. Epub 2008 Jan 7. PubMed PMID: 18180335.
29.146
Weithauser A, Bobbert P, Antoniak S, Bohm A, Rauch BH, Klingel K, Savvatis K, Kroemer HK, Tschope C, Stroux A, Zeichhardt H, Poller W, Mackman N, Schultheiss HP, Rauch U. Protease-activated receptor-2 regulates the innate immune response to viral infection in a coxsackievirus B3-induced myocarditis. J Am Coll Cardiol. 2013 Nov 5;62(19):1737-45. doi: 10.1016/j.jacc.2013.05.076. Epub 2013 Jul 17. PubMed PMID: 23871888; PubMed Central PMCID: PMC4077621.
27.203
Bowles NE, Ni J, Kearney DL, Pauschinger M, Schultheiss HP, McCarthy R, Hare J, Bricker JT, Bowles KR, Towbin JA. Detection of viruses in myocardial tissues by polymerase chain reaction. evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol. 2003 Aug 6;42(3):466-72. doi: 10.1016/s0735-1097(03)00648-x. PubMed PMID: 12906974.
27.203
Kuhl U, Lassner D, Wallaschek N, Gross UM, Krueger GR, Seeberg B, Kaufer BB, Escher F, Poller W, Schultheiss HP. Chromosomally integrated human herpesvirus 6 in heart failure: prevalence and treatment. Eur J Heart Fail. 2015 Jan;17(1):9-19. doi: 10.1002/ejhf.194. Epub 2014 Nov 11. PubMed PMID: 25388833.
17.349
Noutsias M, Rohde M, Goldner K, Block A, Blunert K, Hemaidan L, Hummel M, Blohm JH, Lassner D, Kuhl U, Schultheiss HP, Volk HD, Kotsch K. Expression of functional T-cell markers and T-cell receptor Vbeta repertoire in endomyocardial biopsies from patients presenting with acute myocarditis and dilated cardiomyopathy. Eur J Heart Fail. 2011 Jun;13(6):611-8. doi: 10.1093/eurjhf/hfr014. Epub 2011 Mar 19. PubMed PMID: 21422001.
17.349
Hirsch VG, Schallhorn S, Zwadlo C, Diekmann J, Langer F, Jonigk DD, Kempf T, Schultheiss HP, Bauersachs J. Giant cell myocarditis after first dose of BNT162b2 - a case report. Eur J Heart Fail. 2022 Jul;24(7):1319-1322. doi: 10.1002/ejhf.2590. Epub 2022 Jul 11. PubMed PMID: 35733299; PubMed Central PMCID: PMC9350328.
17.349
Pauschinger M, Rutschow S, Chandrasekharan K, Westermann D, Weitz A, Peter Schwimmbeck L, Zeichhardt H, Poller W, Noutsias M, Li J, Schultheiss HP, Tschope C. Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response. Eur J Heart Fail. 2005 Jun;7(4):444-52. doi: 10.1016/j.ejheart.2004.07.002. PubMed PMID: 15921778.
17.349
Lindner J, Noutsias M, Lassner D, Wenzel J, Schultheiss HP, Kuehl U, Modrow S. Adaptive immune responses against parvovirus B19 in patients with myocardial disease. J Clin Virol. 2009 Jan;44(1):27-32. doi: 10.1016/j.jcv.2008.09.007. Epub 2008 Nov 5. PubMed PMID: 18980860.
14.481
Rutschow S, Li J, Schultheiss HP, Pauschinger M. Myocardial proteases and matrix remodeling in inflammatory heart disease. Cardiovasc Res. 2006 Feb 15;69(3):646-56. doi: 10.1016/j.cardiores.2005.12.009. Epub 2006 Jan 18. PubMed PMID: 16417902.
13.081
Jenke A, Wilk S, Poller W, Eriksson U, Valaperti A, Rauch BH, Stroux A, Liu P, Schultheiss HP, Scheibenbogen C, Skurk C. Adiponectin protects against Toll-like receptor 4-mediated cardiac inflammation and injury. Cardiovasc Res. 2013 Aug 1;99(3):422-31. doi: 10.1093/cvr/cvt118. Epub 2013 May 13. PubMed PMID: 23674516.
13.081
Li J, Schwimmbeck PL, Tschope C, Leschka S, Husmann L, Rutschow S, Reichenbach F, Noutsias M, Kobalz U, Poller W, Spillmann F, Zeichhardt H, Schultheiss HP, Pauschinger M. Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction. Cardiovasc Res. 2002 Nov;56(2):235-47. doi: 10.1016/s0008-6363(02)00546-1. PubMed PMID: 12393094.
13.081
Wenzel P, Kopp S, Gobel S, Jansen T, Geyer M, Hahn F, Kreitner KF, Escher F, Schultheiss HP, Munzel T. Evidence of SARS-CoV-2 mRNA in endomyocardial biopsies of patients with clinically suspected myocarditis tested negative for COVID-19 in nasopharyngeal swab. Cardiovasc Res. 2020 Aug 1;116(10):1661-1663. doi: 10.1093/cvr/cvaa160. No abstract available. PubMed PMID: 32562489; PubMed Central PMCID: PMC7337685.
13.081
Schultheiss HP, Baumeier C, Pietsch H, Bock CT, Poller W, Escher F. Cardiovascular consequences of viral infections: from COVID to other viral diseases. Cardiovasc Res. 2021 Nov 22;117(13):2610-2623. doi: 10.1093/cvr/cvab315. PubMed PMID: 34609508; PubMed Central PMCID: PMC8500164.
13.081
Ebermann L, Piper C, Kuhl U, Klingel K, Schlattner U, Siafarikas N, Zeichhardt H, Schultheiss HP, Dorner A. Impact of myocardial inflammation on cytosolic and mitochondrial creatine kinase activity and expression. Basic Res Cardiol. 2009 May;104(3):247-57. doi: 10.1007/s00395-008-0773-5. Epub 2009 Feb 3. PubMed PMID: 19190956.
12.416
Baumeier C, Escher F, Aleshcheva G, Pietsch H, Schultheiss HP. Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy. Basic Res Cardiol. 2021 Jan 11;116(1):1. doi: 10.1007/s00395-020-00840-w. PubMed PMID: 33432417; PubMed Central PMCID: PMC7801308.
12.416
Savvatis K, Muller I, Frohlich M, Pappritz K, Zietsch C, Hamdani N, Grote K, Schieffer B, Klingel K, Van Linthout S, Linke WA, Schultheiss HP, Tschope C. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis. Basic Res Cardiol. 2014;109(6):449. doi: 10.1007/s00395-014-0449-2. Epub 2014 Oct 25. PubMed PMID: 25344085.
12.416
Pietsch H, Escher F, Aleshcheva G, Baumeier C, Morawietz L, Elsaesser A, Schultheiss HP. Proof of SARS-CoV-2 genomes in endomyocardial biopsy with latency after acute infection. Int J Infect Dis. 2021 Jan;102:70-72. doi: 10.1016/j.ijid.2020.10.012. Epub 2020 Oct 9. PubMed PMID: 33045427; PubMed Central PMCID: PMC7546659.
12.074
Kuhl U, Schultheiss HP. Viral myocarditis: diagnosis, aetiology and management. Drugs. 2009 Jul 9;69(10):1287-302. doi: 10.2165/00003495-200969100-00001. PubMed PMID: 19583449.
11.431
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschope C, Cooper LT Jr, Camici PG. Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document. Circ Heart Fail. 2020 Nov;13(11):e007405. doi: 10.1161/CIRCHEARTFAILURE.120.007405. Epub 2020 Nov 12. PubMed PMID: 33176455; PubMed Central PMCID: PMC7673642.
10.447
Tschope C, Muller I, Xia Y, Savvatis K, Pappritz K, Pinkert S, Lassner D, Heimesaat MM, Spillmann F, Miteva K, Bereswill S, Schultheiss HP, Fechner H, Pieske B, Kuhl U, Van Linthout S. NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 2017 Sep;10(9):e003870. doi: 10.1161/CIRCHEARTFAILURE.117.003870. PubMed PMID: 28912259.
10.447
Muller AM, Bockstahler M, Hristov G, Weiss C, Fischer A, Korkmaz-Icoz S, Giannitsis E, Poller W, Schultheiss HP, Katus HA, Kaya Z. Identification of novel antigens contributing to autoimmunity in cardiovascular diseases. Clin Immunol. 2016 Dec;173:64-75. doi: 10.1016/j.clim.2016.09.003. Epub 2016 Sep 12. PubMed PMID: 27634429.
10.19
Kuhl U, Schultheiss HP. Myocarditis: early biopsy allows for tailored regenerative treatment. Dtsch Arztebl Int. 2012 May;109(20):361-8. doi: 10.3238/arztebl.2012.0361. Epub 2012 May 18. PubMed PMID: 22685492; PubMed Central PMCID: PMC3370379.
8.251
Escher F, Westermann D, Gaub R, Pronk J, Bock T, Al-Saadi N, Kuhl U, Schultheiss HP, Tschope C. Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis. Heart. 2011 May;97(9):709-14. doi: 10.1136/hrt.2010.199489. Epub 2010 Dec 5. PubMed PMID: 21134904.
7.365
Baumeier C, Aleshcheva G, Harms D, Gross U, Hamm C, Assmus B, Westenfeld R, Kelm M, Rammos S, Wenzel P, Munzel T, Elsasser A, Gailani M, Perings C, Bourakkadi A, Flesch M, Kempf T, Bauersachs J, Escher F, Schultheiss HP. Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series. Int J Mol Sci. 2022 Jun 22;23(13):6940. doi: 10.3390/ijms23136940. PubMed PMID: 35805941; PubMed Central PMCID: PMC9266869.
6.208
Escher F, Kuhl U, Lassner D, Poller W, Westermann D, Pieske B, Tschope C, Schultheiss HP. Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy. Clin Res Cardiol. 2016 Dec;105(12):1011-1020. doi: 10.1007/s00392-016-1011-z. Epub 2016 Jun 16. PubMed PMID: 27312326.
6.138
Schultheiss HP, Piper C, Sowade O, Waagstein F, Kapp JF, Wegscheider K, Groetzbach G, Pauschinger M, Escher F, Arbustini E, Siedentop H, Kuehl U. Betaferon in chronic viral cardiomyopathy (BICC) trial: Effects of interferon-beta treatment in patients with chronic viral cardiomyopathy. Clin Res Cardiol. 2016 Sep;105(9):763-73. doi: 10.1007/s00392-016-0986-9. Epub 2016 Apr 25. PubMed PMID: 27112783.
6.138
Koenig T, Kempf T, Schultheiss HP, Cornberg M, Bauersachs J, Schafer A. Fulminant parvovirus B19 myocarditis after chemotherapy: full recovery after antiviral therapy with tenofovir. Clin Res Cardiol. 2022 Feb;111(2):233-236. doi: 10.1007/s00392-021-01955-3. Epub 2021 Oct 20. No abstract available. PubMed PMID: 34669016; PubMed Central PMCID: PMC8816788.
6.138
Poller W, Haas J, Klingel K, Kuhnisch J, Gast M, Kaya Z, Escher F, Kayvanpour E, Degener F, Opgen-Rhein B, Berger F, Mochmann HC, Skurk C, Heidecker B, Schultheiss HP, Monserrat L, Meder B, Landmesser U, Klaassen S. Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene. J Am Heart Assoc. 2020 May 18;9(10):e015289. doi: 10.1161/JAHA.119.015289. Epub 2020 May 15. PubMed PMID: 32410525; PubMed Central PMCID: PMC7660888.
6.106
Coronado MJ, Bruno KA, Blauwet LA, Tschope C, Cunningham MW, Pankuweit S, van Linthout S, Jeon ES, McNamara DM, Krejci J, Bienertova-Vasku J, Douglass EJ, Abston ED, Bucek A, Frisancho JA, Greenaway MS, Hill AR, Schultheiss HP, Cooper LT Jr, Fairweather D. Elevated Sera sST2 Is Associated With Heart Failure in Men </=50 Years Old With Myocarditis. J Am Heart Assoc. 2019 Jan 22;8(2):e008968. doi: 10.1161/JAHA.118.008968. PubMed PMID: 30638108; PubMed Central PMCID: PMC6497352.
6.106
Schultheiss HP, Kuhl U. Why is diagnosis of infectious myocarditis such a challenge? Expert Rev Anti Infect Ther. 2011 Dec;9(12):1093-5. doi: 10.1586/eri.11.135. No abstract available. PubMed PMID: 22114957.
5.854
Antoniak S, Boltzen U, Riad A, Kallwellis-Opara A, Rohde M, Dorner A, Tschope C, Noutsias M, Pauschinger M, Schultheiss HP, Rauch U. Viral myocarditis and coagulopathy: increased tissue factor expression and plasma thrombogenicity. J Mol Cell Cardiol. 2008 Jul;45(1):118-26. doi: 10.1016/j.yjmcc.2008.03.013. Epub 2008 Mar 29. PubMed PMID: 18495150.
5.763
Westermann D, Savvatis K, Schultheiss HP, Tschope C. Immunomodulation and matrix metalloproteinases in viral myocarditis. J Mol Cell Cardiol. 2010 Mar;48(3):468-73. doi: 10.1016/j.yjmcc.2009.08.019. Epub 2009 Sep 1. PubMed PMID: 19729021.
5.763
Fischer R, Poller W, Schultheiss HP, Gotthardt M. CAR-diology--a virus receptor in the healthy and diseased heart. J Mol Med (Berl). 2009 Sep;87(9):879-84. doi: 10.1007/s00109-009-0489-5. Epub 2009 Jun 3. PubMed PMID: 19495568.
5.606
Ebermann L, Wika S, Klumpe I, Hammer E, Klingel K, Lassner D, Volker U, Erben U, Zeichhardt H, Schultheiss HP, Dorner A. The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis. Lab Invest. 2012 Jan;92(1):125-34. doi: 10.1038/labinvest.2011.145. Epub 2011 Oct 3. PubMed PMID: 21968812.
5.502
Gorbea C, Makar KA, Pauschinger M, Pratt G, Bersola JL, Varela J, David RM, Banks L, Huang CH, Li H, Schultheiss HP, Towbin JA, Vallejo JG, Bowles NE. A role for Toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy. J Biol Chem. 2010 Jul 23;285(30):23208-23. doi: 10.1074/jbc.M109.047464. Epub 2010 May 14. PubMed PMID: 20472559; PubMed Central PMCID: PMC2906314.
5.486
Rutschow S, Leschka S, Westermann D, Puhl K, Weitz A, Ladyszenskij L, Jaeger S, Zeichhardt H, Noutsias M, Schultheiss HP, Tschope C, Pauschinger M. Left ventricular enlargement in coxsackievirus-B3 induced chronic myocarditis--ongoing inflammation and an imbalance of the matrix degrading system. Eur J Pharmacol. 2010 Mar 25;630(1-3):145-51. doi: 10.1016/j.ejphar.2009.12.019. Epub 2009 Dec 24. PubMed PMID: 20035743.
5.195
Tschope C, Westermann D, Steendijk P, Noutsias M, Rutschow S, Weitz A, Schwimmbeck PL, Schultheiss HP, Pauschinger M. Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol. Eur J Pharmacol. 2004 May 3;491(2-3):173-9. doi: 10.1016/j.ejphar.2004.03.032. PubMed PMID: 15140634.
5.195
Li J, Leschka S, Rutschow S, Schwimmbeck PL, Husmann L, Noutsias M, Westermann D, Poller W, Zeichhardt H, Klingel K, Tschope C, Schultheiss HP, Pauschinger M. Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis. Eur J Pharmacol. 2007 Jan 5;554(1):60-8. doi: 10.1016/j.ejphar.2006.08.024. Epub 2006 Aug 26. PubMed PMID: 17113076.
5.195
Warraich RS, Noutsias M, Kazak I, Seeberg B, Dunn MJ, Schultheiss HP, Yacoub MH, Kuhl U. Immunoglobulin G3 cardiac myosin autoantibodies correlate with left ventricular dysfunction in patients with dilated cardiomyopathy: immunoglobulin G3 and clinical correlates. Am Heart J. 2002 Jun;143(6):1076-84. doi: 10.1067/mhj.2002.124406. Erratum In: Am Heart J. 2003 Feb;145(2):213.. Kasac Ilkay [corrected to Kazak Ilkay]. PubMed PMID: 12075266.
5.099
Schultheiss HP, Baumeier C, Aleshcheva G, Bock CT, Escher F. Viral Myocarditis-From Pathophysiology to Treatment. J Clin Med. 2021 Nov 11;10(22):5240. doi: 10.3390/jcm10225240. PubMed PMID: 34830522; PubMed Central PMCID: PMC8623269.
4.964
Escher F, Pietsch H, Aleshcheva G, Wenzel P, Fruhwald F, Stumpf C, Westermann D, Bauersachs J, Enseleit F, Ruschitzka F, Nagele H, Laugwitz KL, Haake H, Frey N, Brachmann J, Huber K, Braun-Dullaeus RC, Bergmann MW, Strotmann J, Gronefeld G, Krulls-Munch J, Westenfeld R, Skurk C, Landmesser U, Pieske B, Gross UM, Morawietz L, Schultheiss HP. Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation. J Clin Med. 2020 Aug 19;9(9):2689. doi: 10.3390/jcm9092689. PubMed PMID: 32825201; PubMed Central PMCID: PMC7563288.
4.964
Pauschinger M, Chandrasekharan K, Schultheiss HP. Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system. Heart Fail Rev. 2004 Jan;9(1):21-31. doi: 10.1023/B:HREV.0000011391.81676.3c. PubMed PMID: 14739765.
4.654
Escher F, Kasner M, Kuhl U, Heymer J, Wilkenshoff U, Tschope C, Schultheiss HP. New echocardiographic findings correlate with intramyocardial inflammation in endomyocardial biopsies of patients with acute myocarditis and inflammatory cardiomyopathy. Mediators Inflamm. 2013;2013:875420. doi: 10.1155/2013/875420. Epub 2013 Mar 20. PubMed PMID: 23576857; PubMed Central PMCID: PMC3616345.
4.529
Kuhl U, Schultheiss HP. Viral myocarditis. Swiss Med Wkly. 2014 Oct 2;144:w14010. doi: 10.4414/smw.2014.14010. eCollection 2014. PubMed PMID: 25275335.
4.203
Pauschinger M, Chandrasekharan K, Noutsias M, Kuhl U, Schwimmbeck LP, Schultheiss HP. Viral heart disease: molecular diagnosis, clinical prognosis, and treatment strategies. Med Microbiol Immunol. 2004 May;193(2-3):65-9. doi: 10.1007/s00430-003-0213-y. Epub 2004 Jan 14. PubMed PMID: 14722762.
4.148
Schwimmbeck PL, Bigalke B, Schulze K, Pauschinger M, Kuhl U, Schultheiss HP. The humoral immune response in viral heart disease: characterization and pathophysiological significance of antibodies. Med Microbiol Immunol. 2004 May;193(2-3):115-9. doi: 10.1007/s00430-003-0217-7. Epub 2004 Feb 4. PubMed PMID: 14760530.
4.148
Noutsias M, Pauschinger M, Gross U, Lassner D, Schultheiss HP, Kuhl U. Giant-cell myocarditis in a patient presenting with dilated cardiomyopathy and ventricular tachycardias treated by immunosuppression: a case report. Int J Cardiol. 2008 Aug 18;128(2):e58-9. doi: 10.1016/j.ijcard.2007.04.178. Epub 2007 Aug 17. No abstract available. PubMed PMID: 17707533.
4.039
Kasner M, Sinning D, Escher F, Lassner D, Kuhl U, Schultheiss HP, Tschope C. The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy. Int J Cardiol. 2013 Oct 3;168(3):3023-4. doi: 10.1016/j.ijcard.2013.04.016. Epub 2013 May 20. No abstract available. PubMed PMID: 23701925.
4.039
Kasner M, Aleksandrov A, Escher F, Al-Saadi N, Makowski M, Spillmann F, Genger M, Schultheiss HP, Kuhl U, Pieske B, Morris DA, Noutsias M, Tschope C. Multimodality imaging approach in the diagnosis of chronic myocarditis with preserved left ventricular ejection fraction (MCpEF): The role of 2D speckle-tracking echocardiography. Int J Cardiol. 2017 Sep 15;243:374-378. doi: 10.1016/j.ijcard.2017.05.038. Epub 2017 May 16. PubMed PMID: 28536004.
4.039
Feig MA, Pop C, Bhardwaj G, Sappa PK, Dorr M, Ameling S, Weitmann K, Nauck M, Lehnert K, Beug D, Kuhl U, Schultheiss HP, Volker U, Felix SB, Hammer E. Global plasma protein profiling reveals DCM characteristic protein signatures. J Proteomics. 2019 Oct 30;209:103508. doi: 10.1016/j.jprot.2019.103508. Epub 2019 Aug 30. PubMed PMID: 31476444.
3.855
Savvatis K, van Linthout S, Miteva K, Pappritz K, Westermann D, Schefold JC, Fusch G, Weithauser A, Rauch U, Becher PM, Klingel K, Ringe J, Kurtz A, Schultheiss HP, Tschope C. Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis. PLoS One. 2012;7(7):e41047. doi: 10.1371/journal.pone.0041047. Epub 2012 Jul 17. PubMed PMID: 22815907; PubMed Central PMCID: PMC3398879.
3.752
Miteva K, Haag M, Peng J, Savvatis K, Becher PM, Seifert M, Warstat K, Westermann D, Ringe J, Sittinger M, Schultheiss HP, Tschope C, Van Linthout S. Human cardiac-derived adherent proliferating cells reduce murine acute Coxsackievirus B3-induced myocarditis. PLoS One. 2011;6(12):e28513. doi: 10.1371/journal.pone.0028513. Epub 2011 Dec 9. PubMed PMID: 22174827; PubMed Central PMCID: PMC3235117.
3.752
Aleshcheva G, Pietsch H, Escher F, Schultheiss HP. MicroRNA profiling as a novel diagnostic tool for identification of patients with inflammatory and/or virally induced cardiomyopathies. ESC Heart Fail. 2021 Feb;8(1):408-422. doi: 10.1002/ehf2.13090. Epub 2020 Nov 20. PubMed PMID: 33215881; PubMed Central PMCID: PMC7835602.
3.612
Sotiriou E, Heiner S, Jansen T, Brandt M, Schmidt KH, Kreitner KF, Emrich T, Schultheiss HP, Schulz E, Munzel T, Wenzel P. Therapeutic implications of a combined diagnostic workup including endomyocardial biopsy in an all-comer population of patients with heart failure: a retrospective analysis. ESC Heart Fail. 2018 Aug;5(4):630-641. doi: 10.1002/ehf2.12296. Epub 2018 May 10. PubMed PMID: 29745463; PubMed Central PMCID: PMC6073026.
3.612
Spillmann F, Kuhl U, Van Linthout S, Dominguez F, Escher F, Schultheiss HP, Pieske B, Tschope C. Reversible transition from a hypertrophic to a dilated cardiomyopathy. ESC Heart Fail. 2016 Jun;3(2):138-142. doi: 10.1002/ehf2.12072. Epub 2015 Dec 9. PubMed PMID: 27774273; PubMed Central PMCID: PMC5064744.
3.612
Escher F, Pietsch H, Aleshcheva G, Bock T, Baumeier C, Elsaesser A, Wenzel P, Hamm C, Westenfeld R, Schultheiss M, Gross U, Morawietz L, Schultheiss HP. Detection of viral SARS-CoV-2 genomes and histopathological changes in endomyocardial biopsies. ESC Heart Fail. 2020 Oct;7(5):2440-2447. doi: 10.1002/ehf2.12805. Epub 2020 Jun 12. PubMed PMID: 32529795; PubMed Central PMCID: PMC7307078.
3.612
Tschope C, Van Linthout S, Jager S, Arndt R, Trippel T, Muller I, Elsanhoury A, Rutschow S, Anker SD, Schultheiss HP, Pauschinger M, Spillmann F, Pappritz K. Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis. ESC Heart Fail. 2020 Oct;7(5):2838-2852. doi: 10.1002/ehf2.12887. Epub 2020 Jul 14. PubMed PMID: 32662949; PubMed Central PMCID: PMC7405199.
3.612
Fruhwald F, Lassner D, Fruhwald S, Gross UM, Dapunt O, Schultheiss HP. Immunosuppressive treatment in fulminant myocarditis and gene expression pattern associated with, but no histological confirmation of giant cell myocarditis. ESC Heart Fail. 2017 May;4(2):190-192. doi: 10.1002/ehf2.12130. Epub 2017 Jan 31. PubMed PMID: 28451456; PubMed Central PMCID: PMC5396038.
3.612
Escher F, Modrow S, Sabi T, Kuhl U, Lassner D, Schultheiss HP, Noutsias M. Parvovirus B19 profiles in patients presenting with acute myocarditis and chronic dilated cardiomyopathy. Med Sci Monit. 2008 Dec;14(12):CR589-97. PubMed PMID: 19043365.
3.386
Malz R, Weithauser A, Tschope C, Schultheiss HP, Rauch U. Inhibition of coagulation factor Xa improves myocardial function during CVB3-induced myocarditis. Cardiovasc Ther. 2014 Jun;32(3):113-9. doi: 10.1111/1755-5922.12069. PubMed PMID: 24533719.
3.368
Maleszewski JJ, Orellana VM, Hodge DO, Kuhl U, Schultheiss HP, Cooper LT. Long-term risk of recurrence, morbidity and mortality in giant cell myocarditis. Am J Cardiol. 2015 Jun 15;115(12):1733-8. doi: 10.1016/j.amjcard.2015.03.023. Epub 2015 Mar 24. PubMed PMID: 25882774.
3.133
Dorner A, Kallwellis-Opara A, Pauschinger M, Kuhl U, Schultheiss HP. Cardiac autoantibodies in viral myocarditis. Heart Fail Clin. 2005 Oct;1(3):333-43. doi: 10.1016/j.hfc.2005.06.010. No abstract available. PubMed PMID: 17386858.
2.828
Kuhl U, Schultheiss HP. Myocarditis in children. Heart Fail Clin. 2010 Oct;6(4):483-96, viii-ix. doi: 10.1016/j.hfc.2010.05.009. PubMed PMID: 20869648.
2.828
Montera MW, Marcondes-Braga FG, Simoes MV, Moura LAZ, Fernandes F, Mangine S, Oliveira Junior AC, Souza ALAAG, Ianni BM, Rochitte CE, Mesquita CT, de Azevedo Filho CF, Freitas DCA, Melo DTP, Bocchi EA, Horowitz ESK, Mesquita ET, Oliveira GH, Villacorta H, Rossi Neto JM, Barbosa JMB, Figueiredo Neto JA, Luiz LF, Hajjar LA, Beck-da-Silva L, Campos LAA, Danzmann LC, Bittencourt MI, Garcia MI, Avila MS, Clausell NO, Oliveira NA Jr, Silvestre OM, Souza OF, Mourilhe-Rocha R, Kalil Filho R, Al-Kindi SG, Rassi S, Alves SMM, Ferreira SMA, Rizk SI, Mattos TAC, Barzilai V, Martins WA, Schultheiss HP. Brazilian Society of Cardiology Guideline on Myocarditis - 2022. Arq Bras Cardiol. 2022 Jul;119(1):143-211. doi: 10.36660/abc.20220412. No abstract available. Erratum In: Arq Bras Cardiol. 2022 Dec;119(6):1008. English, Portuguese. PubMed PMID: 35830116; PubMed Central PMCID: PMC9352123.
2.667
Lindner D, Hilbrandt M, Marggraf K, Becher PM, Hilfiker-Kleiner D, Klingel K, Pauschinger M, Schultheiss HP, Tschope C, Westermann D. Protective Function of STAT3 in CVB3-Induced Myocarditis. Cardiol Res Pract. 2012;2012:437623. doi: 10.1155/2012/437623. Epub 2012 May 24. PubMed PMID: 22675647; PubMed Central PMCID: PMC3366200.
1.99
Hudowenz O, Klemm P, Lange U, Rolf A, Schultheiss HP, Hamm C, Muller-Ladner U, Wegner F. Case report of severe PCR-confirmed COVID-19 myocarditis in a European patient manifesting in mid January 2020. Eur Heart J Case Rep. 2020 Oct 21;4(6):1-6. doi: 10.1093/ehjcr/ytaa286. eCollection 2020 Dec. PubMed PMID: 33437916; PubMed Central PMCID: PMC7665439.
Escher F, Tschoepe C, Lassner D, Schultheiss HP. Myocarditis and inflammatory cardiomyopathy: from diagnosis to treatment. Turk Kardiyol Dern Ars. 2015 Dec;43(8):739-48. doi: 10.5543/tkda.2015.47750. PubMed PMID: 26717340.
Jenke A, Schur R, Roger C, Karadeniz Z, Gruger M, Holzhauser L, Savvatis K, Poller W, Schultheiss HP, Landmesser U, Skurk C. Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up-regulating matrix metalloproteinase 9 expression in mice. Physiol Rep. 2017 Dec;5(24):e13523. doi: 10.14814/phy2.13523. PubMed PMID: 29263115; PubMed Central PMCID: PMC5742698.

Data Sources

PubMed
NCBI
SemanticScholar
Web of Science
Human Phenotype ontology
KEGG
IMIB-Arrixaca

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Biomedical Informatics & Bioinformatics Platform
Institute for Bio-health Research of Murcia (IMIB-Arrixaca)
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