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Further information

MYOCARDITIS
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Kuhl, Uwe


Publications

Impact Factor

Cites


ReferenceImpact FactorCitesQuartile
Kuhl U, Pauschinger M, Schwimmbeck PL, Seeberg B, Lober C, Noutsias M, Poller W, Schultheiss HP. Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction. Circulation. 2003 Jun 10;107(22):2793-8. doi: 10.1161/01.CIR.0000072766.67150.51. Epub 2003 May 27. PubMed PMID: 12771005.
39.918
Kuhl U, Pauschinger M, Bock T, Klingel K, Schwimmbeck CP, Seeberg B, Krautwurm L, Poller W, Schultheiss HP, Kandolf R. Parvovirus B19 infection mimicking acute myocardial infarction. Circulation. 2003 Aug 26;108(8):945-50. doi: 10.1161/01.CIR.0000085168.02782.2C. Epub 2003 Aug 18. PubMed PMID: 12925460.
39.918
Holzmann M, Nicko A, Kuhl U, Noutsias M, Poller W, Hoffmann W, Morguet A, Witzenbichler B, Tschope C, Schultheiss HP, Pauschinger M. Complication rate of right ventricular endomyocardial biopsy via the femoral approach: a retrospective and prospective study analyzing 3048 diagnostic procedures over an 11-year period. Circulation. 2008 Oct 21;118(17):1722-8. doi: 10.1161/CIRCULATIONAHA.107.743427. Epub 2008 Oct 6. PubMed PMID: 18838566.
39.918
Kuhl U, Pauschinger M, Seeberg B, Lassner D, Noutsias M, Poller W, Schultheiss HP. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation. 2005 Sep 27;112(13):1965-70. doi: 10.1161/CIRCULATIONAHA.105.548156. Epub 2005 Sep 19. PubMed PMID: 16172268.
39.918
Kuhl U, Pauschinger M, Noutsias M, Seeberg B, Bock T, Lassner D, Poller W, Kandolf R, Schultheiss HP. High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation. 2005 Feb 22;111(7):887-93. doi: 10.1161/01.CIR.0000155616.07901.35. Epub 2005 Feb 7. PubMed PMID: 15699250.
39.918
Schultheiss HP, Kuhl U, Cooper LT. The management of myocarditis. Eur Heart J. 2011 Nov;32(21):2616-25. doi: 10.1093/eurheartj/ehr165. Epub 2011 Jun 23. PubMed PMID: 21705357.
35.855
Gutberlet M, Spors B, Thoma T, Bertram H, Denecke T, Felix R, Noutsias M, Schultheiss HP, Kuhl U. Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence. Radiology. 2008 Feb;246(2):401-9. doi: 10.1148/radiol.2461062179. Epub 2008 Jan 7. PubMed PMID: 18180335.
29.146
Noutsias M, Rohde M, Goldner K, Block A, Blunert K, Hemaidan L, Hummel M, Blohm JH, Lassner D, Kuhl U, Schultheiss HP, Volk HD, Kotsch K. Expression of functional T-cell markers and T-cell receptor Vbeta repertoire in endomyocardial biopsies from patients presenting with acute myocarditis and dilated cardiomyopathy. Eur J Heart Fail. 2011 Jun;13(6):611-8. doi: 10.1093/eurjhf/hfr014. Epub 2011 Mar 19. PubMed PMID: 21422001.
17.349
Kuhl U, Lassner D, Wallaschek N, Gross UM, Krueger GR, Seeberg B, Kaufer BB, Escher F, Poller W, Schultheiss HP. Chromosomally integrated human herpesvirus 6 in heart failure: prevalence and treatment. Eur J Heart Fail. 2015 Jan;17(1):9-19. doi: 10.1002/ejhf.194. Epub 2014 Nov 11. PubMed PMID: 25388833.
17.349
Ebermann L, Piper C, Kuhl U, Klingel K, Schlattner U, Siafarikas N, Zeichhardt H, Schultheiss HP, Dorner A. Impact of myocardial inflammation on cytosolic and mitochondrial creatine kinase activity and expression. Basic Res Cardiol. 2009 May;104(3):247-57. doi: 10.1007/s00395-008-0773-5. Epub 2009 Feb 3. PubMed PMID: 19190956.
12.416
Kuhl U, Schultheiss HP. Viral myocarditis: diagnosis, aetiology and management. Drugs. 2009 Jul 9;69(10):1287-302. doi: 10.2165/00003495-200969100-00001. PubMed PMID: 19583449.
11.431
Muller I, Vogl T, Pappritz K, Miteva K, Savvatis K, Rohde D, Most P, Lassner D, Pieske B, Kuhl U, Van Linthout S, Tschope C. Pathogenic Role of the Damage-Associated Molecular Patterns S100A8 and S100A9 in Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 2017 Nov;10(11):e004125. doi: 10.1161/CIRCHEARTFAILURE.117.004125. PubMed PMID: 29158436.
10.447
Tschope C, Muller I, Xia Y, Savvatis K, Pappritz K, Pinkert S, Lassner D, Heimesaat MM, Spillmann F, Miteva K, Bereswill S, Schultheiss HP, Fechner H, Pieske B, Kuhl U, Van Linthout S. NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 2017 Sep;10(9):e003870. doi: 10.1161/CIRCHEARTFAILURE.117.003870. PubMed PMID: 28912259.
10.447
Kuhl U, Schultheiss HP. Myocarditis: early biopsy allows for tailored regenerative treatment. Dtsch Arztebl Int. 2012 May;109(20):361-8. doi: 10.3238/arztebl.2012.0361. Epub 2012 May 18. PubMed PMID: 22685492; PubMed Central PMCID: PMC3370379.
8.251
Escher F, Westermann D, Gaub R, Pronk J, Bock T, Al-Saadi N, Kuhl U, Schultheiss HP, Tschope C. Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis. Heart. 2011 May;97(9):709-14. doi: 10.1136/hrt.2010.199489. Epub 2010 Dec 5. PubMed PMID: 21134904.
7.365
Rottgen R, Christiani R, Freyhardt P, Gutberlet M, Schultheiss HP, Hamm B, Kuhl U. Magnetic resonance imaging findings in acute myocarditis and correlation with immunohistological parameters. Eur Radiol. 2011 Jun;21(6):1259-66. doi: 10.1007/s00330-010-2022-1. Epub 2010 Nov 30. PubMed PMID: 21116631; PubMed Central PMCID: PMC3088804.
7.034
Escher F, Kuhl U, Lassner D, Poller W, Westermann D, Pieske B, Tschope C, Schultheiss HP. Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy. Clin Res Cardiol. 2016 Dec;105(12):1011-1020. doi: 10.1007/s00392-016-1011-z. Epub 2016 Jun 16. PubMed PMID: 27312326.
6.138
Schultheiss HP, Kuhl U. Why is diagnosis of infectious myocarditis such a challenge? Expert Rev Anti Infect Ther. 2011 Dec;9(12):1093-5. doi: 10.1586/eri.11.135. No abstract available. PubMed PMID: 22114957.
5.854
Elsanhoury A, Kuhl U, Stautner B, Klein O, Krannich A, Morris D, Willner M, Jankowska E, Klingel K, Van Linthout S, Tschope C. The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention. Viruses. 2022 Jan 31;14(2):299. doi: 10.3390/v14020299. PubMed PMID: 35215893; PubMed Central PMCID: PMC8879301.
5.818
Warraich RS, Noutsias M, Kazak I, Seeberg B, Dunn MJ, Schultheiss HP, Yacoub MH, Kuhl U. Immunoglobulin G3 cardiac myosin autoantibodies correlate with left ventricular dysfunction in patients with dilated cardiomyopathy: immunoglobulin G3 and clinical correlates. Am Heart J. 2002 Jun;143(6):1076-84. doi: 10.1067/mhj.2002.124406. Erratum In: Am Heart J. 2003 Feb;145(2):213.. Kasac Ilkay [corrected to Kazak Ilkay]. PubMed PMID: 12075266.
5.099
Escher F, Kasner M, Kuhl U, Heymer J, Wilkenshoff U, Tschope C, Schultheiss HP. New echocardiographic findings correlate with intramyocardial inflammation in endomyocardial biopsies of patients with acute myocarditis and inflammatory cardiomyopathy. Mediators Inflamm. 2013;2013:875420. doi: 10.1155/2013/875420. Epub 2013 Mar 20. PubMed PMID: 23576857; PubMed Central PMCID: PMC3616345.
4.529
Kuhl U, Schultheiss HP. Viral myocarditis. Swiss Med Wkly. 2014 Oct 2;144:w14010. doi: 10.4414/smw.2014.14010. eCollection 2014. PubMed PMID: 25275335.
4.203
Schwimmbeck PL, Bigalke B, Schulze K, Pauschinger M, Kuhl U, Schultheiss HP. The humoral immune response in viral heart disease: characterization and pathophysiological significance of antibodies. Med Microbiol Immunol. 2004 May;193(2-3):115-9. doi: 10.1007/s00430-003-0217-7. Epub 2004 Feb 4. PubMed PMID: 14760530.
4.148
Pauschinger M, Chandrasekharan K, Noutsias M, Kuhl U, Schwimmbeck LP, Schultheiss HP. Viral heart disease: molecular diagnosis, clinical prognosis, and treatment strategies. Med Microbiol Immunol. 2004 May;193(2-3):65-9. doi: 10.1007/s00430-003-0213-y. Epub 2004 Jan 14. PubMed PMID: 14722762.
4.148
Noutsias M, Pauschinger M, Gross U, Lassner D, Schultheiss HP, Kuhl U. Giant-cell myocarditis in a patient presenting with dilated cardiomyopathy and ventricular tachycardias treated by immunosuppression: a case report. Int J Cardiol. 2008 Aug 18;128(2):e58-9. doi: 10.1016/j.ijcard.2007.04.178. Epub 2007 Aug 17. No abstract available. PubMed PMID: 17707533.
4.039
Kasner M, Aleksandrov A, Escher F, Al-Saadi N, Makowski M, Spillmann F, Genger M, Schultheiss HP, Kuhl U, Pieske B, Morris DA, Noutsias M, Tschope C. Multimodality imaging approach in the diagnosis of chronic myocarditis with preserved left ventricular ejection fraction (MCpEF): The role of 2D speckle-tracking echocardiography. Int J Cardiol. 2017 Sep 15;243:374-378. doi: 10.1016/j.ijcard.2017.05.038. Epub 2017 May 16. PubMed PMID: 28536004.
4.039
Kasner M, Sinning D, Escher F, Lassner D, Kuhl U, Schultheiss HP, Tschope C. The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy. Int J Cardiol. 2013 Oct 3;168(3):3023-4. doi: 10.1016/j.ijcard.2013.04.016. Epub 2013 May 20. No abstract available. PubMed PMID: 23701925.
4.039
Feig MA, Pop C, Bhardwaj G, Sappa PK, Dorr M, Ameling S, Weitmann K, Nauck M, Lehnert K, Beug D, Kuhl U, Schultheiss HP, Volker U, Felix SB, Hammer E. Global plasma protein profiling reveals DCM characteristic protein signatures. J Proteomics. 2019 Oct 30;209:103508. doi: 10.1016/j.jprot.2019.103508. Epub 2019 Aug 30. PubMed PMID: 31476444.
3.855
Pappritz K, Lin J, El-Shafeey M, Fechner H, Kuhl U, Alogna A, Spillmann F, Elsanhoury A, Schulz R, Tschope C, Van Linthout S. Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis. ESC Heart Fail. 2022 Apr;9(2):925-941. doi: 10.1002/ehf2.13845. Epub 2022 Feb 17. PubMed PMID: 35178861; PubMed Central PMCID: PMC8934990.
3.612
Spillmann F, Kuhl U, Van Linthout S, Dominguez F, Escher F, Schultheiss HP, Pieske B, Tschope C. Reversible transition from a hypertrophic to a dilated cardiomyopathy. ESC Heart Fail. 2016 Jun;3(2):138-142. doi: 10.1002/ehf2.12072. Epub 2015 Dec 9. PubMed PMID: 27774273; PubMed Central PMCID: PMC5064744.
3.612
Ferrero P, Piazza I, Kuhl U, Grosu A, Tschope C, Senni M. QRS fragmentation as a possible electrocardiographic diagnostic marker in patients with acute myocarditis: preliminary histopathological validation. ESC Heart Fail. 2020 Oct;7(5):2527-2533. doi: 10.1002/ehf2.12821. Epub 2020 Jun 19. PubMed PMID: 32562382; PubMed Central PMCID: PMC7524046.
3.612
Blaschke F, Lacour P, Dang PL, Parwani AS, Hohendanner F, Walter T, Klingel K, Kuhl U, Heinzel FR, Sherif M, Boldt LH, Pieske B, Tschope C. Wearable cardioverter-defibrillator: friend or foe in suspected myocarditis? ESC Heart Fail. 2021 Aug;8(4):2591-2596. doi: 10.1002/ehf2.13340. Epub 2021 May 1. PubMed PMID: 33932118; PubMed Central PMCID: PMC8318471.
3.612
Muller I, Vogl T, Kuhl U, Krannich A, Banks A, Trippel T, Noutsias M, Maisel AS, van Linthout S, Tschope C. Serum alarmin S100A8/S100A9 levels and its potential role as biomarker in myocarditis. ESC Heart Fail. 2020 Aug;7(4):1442-1451. doi: 10.1002/ehf2.12760. Epub 2020 May 28. PubMed PMID: 32462801; PubMed Central PMCID: PMC7373886.
3.612
Van Linthout S, Elsanhoury A, Klein O, Sosnowski M, Miteva K, Lassner D, Abou-El-Enein M, Pieske B, Kuhl U, Tschope C. Telbivudine in chronic lymphocytic myocarditis and human parvovirus B19 transcriptional activity. ESC Heart Fail. 2018 Oct;5(5):818-829. doi: 10.1002/ehf2.12341. Epub 2018 Aug 11. PubMed PMID: 30099854; PubMed Central PMCID: PMC6165949.
3.612
Escher F, Modrow S, Sabi T, Kuhl U, Lassner D, Schultheiss HP, Noutsias M. Parvovirus B19 profiles in patients presenting with acute myocarditis and chronic dilated cardiomyopathy. Med Sci Monit. 2008 Dec;14(12):CR589-97. PubMed PMID: 19043365.
3.386
Maleszewski JJ, Orellana VM, Hodge DO, Kuhl U, Schultheiss HP, Cooper LT. Long-term risk of recurrence, morbidity and mortality in giant cell myocarditis. Am J Cardiol. 2015 Jun 15;115(12):1733-8. doi: 10.1016/j.amjcard.2015.03.023. Epub 2015 Mar 24. PubMed PMID: 25882774.
3.133
Kuhl U. Antiviral treatment of myocarditis and acute dilated cardiomyopathy. Heart Fail Clin. 2005 Oct;1(3):467-74. doi: 10.1016/j.hfc.2005.06.014. No abstract available. PubMed PMID: 17386869.
2.828
Dorner A, Kallwellis-Opara A, Pauschinger M, Kuhl U, Schultheiss HP. Cardiac autoantibodies in viral myocarditis. Heart Fail Clin. 2005 Oct;1(3):333-43. doi: 10.1016/j.hfc.2005.06.010. No abstract available. PubMed PMID: 17386858.
2.828
Kuhl U, Schultheiss HP. Myocarditis in children. Heart Fail Clin. 2010 Oct;6(4):483-96, viii-ix. doi: 10.1016/j.hfc.2010.05.009. PubMed PMID: 20869648.
2.828
Tschope C, Kuhl U. [Myocarditis and inflammatory cardiomyopathy--current treatment options]. Dtsch Med Wochenschr. 2016 Jan;141(2):95-102. doi: 10.1055/s-0041-107710. Epub 2016 Jan 22. German. PubMed PMID: 26800069.
0.653
Tschope C, Van Linthout S, Spillmann F, Posch MG, Reinke P, Volk HD, Elsanhoury A, Kuhl U. Targeting CD20+ B-lymphocytes in inflammatory dilated cardiomyopathy with rituximab improves clinical course: a case series. Eur Heart J Case Rep. 2019 Sep 1;3(3):ytz131. doi: 10.1093/ehjcr/ytz131. PubMed PMID: 31365055; PubMed Central PMCID: PMC6764574.
Reibis R, Kuhl U, Salzwedel A, Rasawieh M, Eichler S, Wegscheider K, Voller H. Return to work in heart failure patients with suspected viral myocarditis. SAGE Open Med. 2017 Dec 12;5:2050312117744978. doi: 10.1177/2050312117744978. eCollection 2017. PubMed PMID: 29276589; PubMed Central PMCID: PMC5734435.
Dominguez F, Kuhl U, Pieske B, Garcia-Pavia P, Tschope C. Update on Myocarditis and Inflammatory Cardiomyopathy: Reemergence of Endomyocardial Biopsy. Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):178-87. doi: 10.1016/j.rec.2015.10.015. Epub 2016 Jan 12. PubMed PMID: 26795929.

Data Sources

IMIB-Arrixaca

Address

Biomedical Informatics & Bioinformatics Platform
Institute for Bio-health Research of Murcia (IMIB-Arrixaca)
Carretera Buenavista s/n, 30120
El Palmar, Murcia, Spain

Phones

+34 968885229
+34 968885239
+34 968885249