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Thurner L, Kessel C, Fadle N, Regitz E, Seidel F, Kindermann I, Lohse S, Kos I, Tschope C, Kheiroddin P, Kiblboeck D, Hoffmann MC, Bette B, Carbon G, Cetin O, Preuss KD, Christofyllakis K, Bittenbring JT, Pickardt T, Fischer Y, Thiele H, Baldus S, Stangl K, Steiner S, Gietzen F, Kerber S, Deneke T, Jellinghaus S, Linke A, Ibrahim K, Grabmaier U, Massberg S, Thilo C, Greulich S, Gawaz M, Mayatepek E, Meyer-Dobkowitz L, Kindermann M, Birk E, Birk M, Lainscak M, Foell D, Lepper PM, Bals R, Krawczyk M, Mevorach D, Hasin T, Keren A, Kabesch M, Abdul-Khaliq H, Smola S, Bewarder M, Thurner B, Bohm M, Pfeifer J, Klingel K. IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination. N Engl J Med. 2022 Oct 20;387(16):1524-1527. doi: 10.1056/NEJMc2205667. Epub 2022 Sep 21. No abstract available. PubMed PMID: 36130012; PubMed Central PMCID: PMC9513854.
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176.079
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Bock CT, Klingel K, Kandolf R. Human parvovirus B19-associated myocarditis. N Engl J Med. 2010 Apr 1;362(13):1248-9. doi: 10.1056/NEJMc0911362. No abstract available. PubMed PMID: 20357294.
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176.079
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Tschope C, Ammirati E, Bozkurt B, Caforio ALP, Cooper LT, Felix SB, Hare JM, Heidecker B, Heymans S, Hubner N, Kelle S, Klingel K, Maatz H, Parwani AS, Spillmann F, Starling RC, Tsutsui H, Seferovic P, Van Linthout S. Myocarditis and inflammatory cardiomyopathy: current evidence and future directions. Nat Rev Cardiol. 2021 Mar;18(3):169-193. doi: 10.1038/s41569-020-00435-x. Epub 2020 Oct 12. PubMed PMID: 33046850; PubMed Central PMCID: PMC7548534.
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49.421
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Westermann D, Savvatis K, Lindner D, Zietsch C, Becher PM, Hammer E, Heimesaat MM, Bereswill S, Volker U, Escher F, Riad A, Plendl J, Klingel K, Poller W, Schultheiss HP, Tschope C. Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation. 2011 Nov 8;124(19):2082-93. doi: 10.1161/CIRCULATIONAHA.111.035964. Epub 2011 Oct 10. PubMed PMID: 21986287.
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39.918
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Mahrholdt H, Goedecke C, Wagner A, Meinhardt G, Athanasiadis A, Vogelsberg H, Fritz P, Klingel K, Kandolf R, Sechtem U. Cardiovascular magnetic resonance assessment of human myocarditis: a comparison to histology and molecular pathology. Circulation. 2004 Mar 16;109(10):1250-8. doi: 10.1161/01.CIR.0000118493.13323.81. Epub 2004 Mar 1. PubMed PMID: 14993139.
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39.918
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Florian A, Ludwig A, Ong P, Klingel K, Kandolf R, Bornemann A, Sechtem U, Yilmaz A. Cause of cardiac disease in a female carrier of Duchenne muscular dystrophy: myocarditis versus genetic cardiomyopathy without skeletal myopathy? Circulation. 2014 May 6;129(18):e482-4. doi: 10.1161/CIRCULATIONAHA.113.006891. No abstract available. PubMed PMID: 24799508.
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39.918
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Yilmaz A, Kindermann I, Kindermann M, Mahfoud F, Ukena C, Athanasiadis A, Hill S, Mahrholdt H, Voehringer M, Schieber M, Klingel K, Kandolf R, Bohm M, Sechtem U. Comparative evaluation of left and right ventricular endomyocardial biopsy: differences in complication rate and diagnostic performance. Circulation. 2010 Aug 31;122(9):900-9. doi: 10.1161/CIRCULATIONAHA.109.924167. Epub 2010 Aug 16. PubMed PMID: 20713901.
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39.918
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Bockstahler M, Fischer A, Goetzke CC, Neumaier HL, Sauter M, Kespohl M, Muller AM, Meckes C, Salbach C, Schenk M, Heuser A, Landmesser U, Weiner J, Meder B, Lehmann L, Kratzer A, Klingel K, Katus HA, Kaya Z, Beling A. Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation. Circulation. 2020 Jun 9;141(23):1885-1902. doi: 10.1161/CIRCULATIONAHA.119.043171. Epub 2020 Mar 12. PubMed PMID: 32160764.
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39.918
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Pinkert S, Westermann D, Wang X, Klingel K, Dorner A, Savvatis K, Grossl T, Krohn S, Tschope C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H. Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor. Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23. PubMed PMID: 19933937.
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39.918
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Mahrholdt H, Wagner A, Deluigi CC, Kispert E, Hager S, Meinhardt G, Vogelsberg H, Fritz P, Dippon J, Bock CT, Klingel K, Kandolf R, Sechtem U. Presentation, patterns of myocardial damage, and clinical course of viral myocarditis. Circulation. 2006 Oct 10;114(15):1581-90. doi: 10.1161/CIRCULATIONAHA.105.606509. Epub 2006 Oct 2. PubMed PMID: 17015795.
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39.918
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Kuhl U, Pauschinger M, Bock T, Klingel K, Schwimmbeck CP, Seeberg B, Krautwurm L, Poller W, Schultheiss HP, Kandolf R. Parvovirus B19 infection mimicking acute myocardial infarction. Circulation. 2003 Aug 26;108(8):945-50. doi: 10.1161/01.CIR.0000085168.02782.2C. Epub 2003 Aug 18. PubMed PMID: 12925460.
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39.918
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Rahnefeld A, Klingel K, Schuermann A, Diny NL, Althof N, Lindner A, Bleienheuft P, Savvatis K, Respondek D, Opitz E, Ketscher L, Sauter M, Seifert U, Tschope C, Poller W, Knobeloch KP, Voigt A. Ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) in host defense against heart failure in a mouse model of virus-induced cardiomyopathy. Circulation. 2014 Oct 28;130(18):1589-600. doi: 10.1161/CIRCULATIONAHA.114.009847. Epub 2014 Aug 27. PubMed PMID: 25165091.
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39.918
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Kindermann I, Kindermann M, Kandolf R, Klingel K, Bultmann B, Muller T, Lindinger A, Bohm M. Predictors of outcome in patients with suspected myocarditis. Circulation. 2008 Aug 5;118(6):639-48. doi: 10.1161/CIRCULATIONAHA.108.769489. Epub 2008 Jul 21. Erratum In: Circulation.2008 Sep 16;118(12): e493. PubMed PMID: 18645053.
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39.918
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Baccouche H, Mahrholdt H, Meinhardt G, Merher R, Voehringer M, Hill S, Klingel K, Kandolf R, Sechtem U, Yilmaz A. Diagnostic synergy of non-invasive cardiovascular magnetic resonance and invasive endomyocardial biopsy in troponin-positive patients without coronary artery disease. Eur Heart J. 2009 Dec;30(23):2869-79. doi: 10.1093/eurheartj/ehp328. Epub 2009 Aug 20. PubMed PMID: 19696191.
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35.855
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Mahfoud F, Gartner B, Kindermann M, Ukena C, Gadomski K, Klingel K, Kandolf R, Bohm M, Kindermann I. Virus serology in patients with suspected myocarditis: utility or futility? Eur Heart J. 2011 Apr;32(7):897-903. doi: 10.1093/eurheartj/ehq493. Epub 2011 Jan 8. PubMed PMID: 21217143.
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35.855
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Caforio AL, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, Fu M, Helio T, Heymans S, Jahns R, Klingel K, Linhart A, Maisch B, McKenna W, Mogensen J, Pinto YM, Ristic A, Schultheiss HP, Seggewiss H, Tavazzi L, Thiene G, Yilmaz A, Charron P, Elliott PM; European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi: 10.1093/eurheartj/eht210. Epub 2013 Jul 3. PubMed PMID: 23824828.
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35.855
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Klingel K, Poml P, Strunk J, Werthmann ML. Lethal enterovirus myocarditis in a patient with granulomatosis with polyangiitis following rituximab and high-dose steroid therapy. Eur Heart J. 2021 Jun 21;42(24):2401. doi: 10.1093/eurheartj/ehab269. No abstract available. PubMed PMID: 34021319.
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35.855
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Klingel K, Lang N, Kandolf R, Netz H. Lymphofollicular myocarditis: an unknown cause of terminal heart failure. Eur Heart J. 2010 Apr;31(7):892. doi: 10.1093/eurheartj/ehp560. Epub 2009 Dec 21. No abstract available. PubMed PMID: 20028695.
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35.855
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Weckbach LT, Schweizer L, Kraechan A, Bieber S, Ishikawa-Ankerhold H, Hausleiter J, Massberg S, Straub T, Klingel K, Grabmaier U, Zwiebel M, Mann M, Schulz C; EMB Study Group. Association of Complement and MAPK Activation With SARS-CoV-2-Associated Myocardial Inflammation. JAMA Cardiol. 2022 Mar 1;7(3):286-297. doi: 10.1001/jamacardio.2021.5133. PubMed PMID: 34910083; PubMed Central PMCID: PMC8674808.
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30.154
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Baessler B, Luecke C, Lurz J, Klingel K, Das A, von Roeder M, de Waha-Thiele S, Besler C, Rommel KP, Maintz D, Gutberlet M, Thiele H, Lurz P. Cardiac MRI and Texture Analysis of Myocardial T1 and T2 Maps in Myocarditis with Acute versus Chronic Symptoms of Heart Failure. Radiology. 2019 Sep;292(3):608-617. doi: 10.1148/radiol.2019190101. Epub 2019 Jul 30. PubMed PMID: 31361205.
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29.146
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Baessler B, Luecke C, Lurz J, Klingel K, von Roeder M, de Waha S, Besler C, Maintz D, Gutberlet M, Thiele H, Lurz P. Cardiac MRI Texture Analysis of T1 and T2 Maps in Patients with Infarctlike Acute Myocarditis. Radiology. 2018 Nov;289(2):357-365. doi: 10.1148/radiol.2018180411. Epub 2018 Aug 7. PubMed PMID: 30084736.
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29.146
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Shi Y, Chen C, Lisewski U, Wrackmeyer U, Radke M, Westermann D, Sauter M, Tschope C, Poller W, Klingel K, Gotthardt M. Cardiac deletion of the Coxsackievirus-adenovirus receptor abolishes Coxsackievirus B3 infection and prevents myocarditis in vivo. J Am Coll Cardiol. 2009 Apr 7;53(14):1219-26. doi: 10.1016/j.jacc.2008.10.064. PubMed PMID: 19341864.
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27.203
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Weithauser A, Bobbert P, Antoniak S, Bohm A, Rauch BH, Klingel K, Savvatis K, Kroemer HK, Tschope C, Stroux A, Zeichhardt H, Poller W, Mackman N, Schultheiss HP, Rauch U. Protease-activated receptor-2 regulates the innate immune response to viral infection in a coxsackievirus B3-induced myocarditis. J Am Coll Cardiol. 2013 Nov 5;62(19):1737-45. doi: 10.1016/j.jacc.2013.05.076. Epub 2013 Jul 17. PubMed PMID: 23871888; PubMed Central PMCID: PMC4077621.
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27.203
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Grun S, Schumm J, Greulich S, Wagner A, Schneider S, Bruder O, Kispert EM, Hill S, Ong P, Klingel K, Kandolf R, Sechtem U, Mahrholdt H. Long-term follow-up of biopsy-proven viral myocarditis: predictors of mortality and incomplete recovery. J Am Coll Cardiol. 2012 May 1;59(18):1604-15. doi: 10.1016/j.jacc.2012.01.007. Epub 2012 Feb 22. PubMed PMID: 22365425.
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27.203
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Lurz P, Luecke C, Eitel I, Fohrenbach F, Frank C, Grothoff M, de Waha S, Rommel KP, Lurz JA, Klingel K, Kandolf R, Schuler G, Thiele H, Gutberlet M. Comprehensive Cardiac Magnetic Resonance Imaging in Patients With Suspected Myocarditis: The MyoRacer-Trial. J Am Coll Cardiol. 2016 Apr 19;67(15):1800-1811. doi: 10.1016/j.jacc.2016.02.013. PubMed PMID: 27081020.
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27.203
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Brambatti M, Matassini MV, Adler ED, Klingel K, Camici PG, Ammirati E. Eosinophilic Myocarditis: Characteristics, Treatment, and Outcomes. J Am Coll Cardiol. 2017 Nov 7;70(19):2363-2375. doi: 10.1016/j.jacc.2017.09.023. PubMed PMID: 29096807.
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27.203
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Kindermann I, Barth C, Mahfoud F, Ukena C, Lenski M, Yilmaz A, Klingel K, Kandolf R, Sechtem U, Cooper LT, Bohm M. Update on myocarditis. J Am Coll Cardiol. 2012 Feb 28;59(9):779-92. doi: 10.1016/j.jacc.2011.09.074. PubMed PMID: 22361396.
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27.203
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Szalay G, Sauter M, Haberland M, Zuegel U, Steinmeyer A, Kandolf R, Klingel K. Osteopontin: a fibrosis-related marker molecule in cardiac remodeling of enterovirus myocarditis in the susceptible host. Circ Res. 2009 Apr 10;104(7):851-9. doi: 10.1161/CIRCRESAHA.109.193805. Epub 2009 Feb 26. PubMed PMID: 19246678.
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23.213
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Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019 Feb 4;216(2):350-368. doi: 10.1084/jem.20181102. Epub 2019 Jan 15. PubMed PMID: 30647120; PubMed Central PMCID: PMC6363424.
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17.579
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Heidecker B, Dagan N, Balicer R, Eriksson U, Rosano G, Coats A, Tschope C, Kelle S, Poland GA, Frustaci A, Klingel K, Martin P, Hare JM, Cooper LT, Pantazis A, Imazio M, Prasad S, Luscher TF. Myocarditis following COVID-19 vaccine: incidence, presentation, diagnosis, pathophysiology, therapy, and outcomes put into perspective. A clinical consensus document supported by the Heart Failure Association of the European Society of Cardiology (ESC) and the ESC Working Group on Myocardial and Pericardial Diseases. Eur J Heart Fail. 2022 Nov;24(11):2000-2018. doi: 10.1002/ejhf.2669. Epub 2022 Oct 6. PubMed PMID: 36065751; PubMed Central PMCID: PMC9538893.
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17.349
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Seferovic PM, Tsutsui H, McNamara DM, Ristic AD, Basso C, Bozkurt B, Cooper LT Jr, Filippatos G, Ide T, Inomata T, Klingel K, Linhart A, Lyon AR, Mehra MR, Polovina M, Milinkovic I, Nakamura K, Anker SD, Veljic I, Ohtani T, Okumura T, Thum T, Tschope C, Rosano G, Coats AJS, Starling RC. Heart Failure Association of the ESC, Heart Failure Society of America and Japanese Heart Failure Society Position statement on endomyocardial biopsy. Eur J Heart Fail. 2021 Jun;23(6):854-871. doi: 10.1002/ejhf.2190. Epub 2021 May 19. Erratum In: Eur J Heart Fail. 2022 Apr;24(4):732. PubMed PMID: 34010472.
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17.349
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Van Linthout S, Klingel K, Tschope C. SARS-CoV-2-related myocarditis-like syndromes Shakespeare's question: what's in a name? Eur J Heart Fail. 2020 Jun;22(6):922-925. doi: 10.1002/ejhf.1899. Epub 2020 Jun 20. No abstract available. PubMed PMID: 32430971; PubMed Central PMCID: PMC7276849.
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17.349
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Besler C, Urban D, Watzka S, Lang D, Rommel KP, Kandolf R, Klingel K, Thiele H, Linke A, Schuler G, Adams V, Lurz P. Endomyocardial miR-133a levels correlate with myocardial inflammation, improved left ventricular function, and clinical outcome in patients with inflammatory cardiomyopathy. Eur J Heart Fail. 2016 Dec;18(12):1442-1451. doi: 10.1002/ejhf.579. Epub 2016 Jun 13. PubMed PMID: 27292200.
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17.349
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Lurz P, Eitel I, Adam J, Steiner J, Grothoff M, Desch S, Fuernau G, de Waha S, Sareban M, Luecke C, Klingel K, Kandolf R, Schuler G, Gutberlet M, Thiele H. Diagnostic performance of CMR imaging compared with EMB in patients with suspected myocarditis. JACC Cardiovasc Imaging. 2012 May;5(5):513-24. doi: 10.1016/j.jcmg.2011.11.022. PubMed PMID: 22595159.
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16.051
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Hakacova N, Klingel K, Kandolf R, Engdahl E, Fogdell-Hahn A, Higgins T. First therapeutic use of Artesunate in treatment of human herpesvirus 6B myocarditis in a child. J Clin Virol. 2013 Jun;57(2):157-60. doi: 10.1016/j.jcv.2013.02.005. Epub 2013 Mar 6. PubMed PMID: 23473961.
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14.481
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Althof N, Goetzke CC, Kespohl M, Voss K, Heuser A, Pinkert S, Kaya Z, Klingel K, Beling A. The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis. EMBO Mol Med. 2018 Feb;10(2):200-218. doi: 10.15252/emmm.201708089. PubMed PMID: 29295868; PubMed Central PMCID: PMC5801517.
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14.26
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Weidenbach M, Springer T, Daehnert I, Klingel K, Doll S, Janousek J. Giant cell myocarditis mimicking idiopathic fascicular ventricular tachycardia. J Heart Lung Transplant. 2008 Feb;27(2):238-41. doi: 10.1016/j.healun.2007.10.014. PubMed PMID: 18267234.
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13.569
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Pinkert S, Pryshliak M, Pappritz K, Knoch K, Hazini A, Dieringer B, Schaar K, Dong F, Hinze L, Lin J, Lassner D, Klopfleisch R, Solimena M, Tschope C, Kaya Z, El-Shafeey M, Beling A, Kurreck J, Van Linthout S, Klingel K, Fechner H. Development of a new mouse model for coxsackievirus-induced myocarditis by attenuating coxsackievirus B3 virulence in the pancreas. Cardiovasc Res. 2020 Aug 1;116(10):1756-1766. doi: 10.1093/cvr/cvz259. PubMed PMID: 31598635.
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13.081
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Maier HJ, Schips TG, Wietelmann A, Kruger M, Brunner C, Sauter M, Klingel K, Bottger T, Braun T, Wirth T. Cardiomyocyte-specific IkappaB kinase (IKK)/NF-kappaB activation induces reversible inflammatory cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11794-9. doi: 10.1073/pnas.1116584109. Epub 2012 Jul 2. PubMed PMID: 22753500; PubMed Central PMCID: PMC3406816.
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12.779
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Ammirati E, Raimondi F, Piriou N, Sardo Infirri L, Mohiddin SA, Mazzanti A, Shenoy C, Cavallari UA, Imazio M, Aquaro GD, Olivotto I, Pedrotti P, Sekhri N, Van de Heyning CM, Broeckx G, Peretto G, Guttmann O, Dellegrottaglie S, Scatteia A, Gentile P, Merlo M, Goldberg RI, Reyentovich A, Sciamanna C, Klaassen S, Poller W, Trankle CR, Abbate A, Keren A, Horowitz-Cederboim S, Cadrin-Tourigny J, Tadros R, Annoni GA, Bonoldi E, Toquet C, Marteau L, Probst V, Trochu JN, Kissopoulou A, Grosu A, Kukavica D, Trancuccio A, Gil C, Tini G, Pedrazzini M, Torchio M, Sinagra G, Gimeno JR, Bernasconi D, Valsecchi MG, Klingel K, Adler ED, Camici PG, Cooper LT Jr. Acute Myocarditis Associated With Desmosomal Gene Variants. JACC Heart Fail. 2022 Oct;10(10):714-727. doi: 10.1016/j.jchf.2022.06.013. Epub 2022 Sep 7. PubMed PMID: 36175056.
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12.544
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Goetzke CC, Althof N, Neumaier HL, Heuser A, Kaya Z, Kespohl M, Klingel K, Beling A. Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection. Basic Res Cardiol. 2021 Feb 1;116(1):7. doi: 10.1007/s00395-021-00848-w. PubMed PMID: 33523326; PubMed Central PMCID: PMC7851025.
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12.416
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Kraft L, Erdenesukh T, Sauter M, Tschope C, Klingel K. Blocking the IL-1beta signalling pathway prevents chronic viral myocarditis and cardiac remodeling. Basic Res Cardiol. 2019 Jan 23;114(2):11. doi: 10.1007/s00395-019-0719-0. PubMed PMID: 30673858.
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12.416
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Ebermann L, Piper C, Kuhl U, Klingel K, Schlattner U, Siafarikas N, Zeichhardt H, Schultheiss HP, Dorner A. Impact of myocardial inflammation on cytosolic and mitochondrial creatine kinase activity and expression. Basic Res Cardiol. 2009 May;104(3):247-57. doi: 10.1007/s00395-008-0773-5. Epub 2009 Feb 3. PubMed PMID: 19190956.
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12.416
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Voigt A, Bartel K, Egerer K, Trimpert C, Feist E, Gericke C, Kandolf R, Klingel K, Kuckelkorn U, Stangl K, Felix SB, Baumann G, Kloetzel PM, Staudt A. Humoral anti-proteasomal autoimmunity in dilated cardiomyopathy. Basic Res Cardiol. 2010 Jan;105(1):9-18. doi: 10.1007/s00395-009-0061-z. PubMed PMID: 19760349.
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12.416
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Savvatis K, Muller I, Frohlich M, Pappritz K, Zietsch C, Hamdani N, Grote K, Schieffer B, Klingel K, Van Linthout S, Linke WA, Schultheiss HP, Tschope C. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis. Basic Res Cardiol. 2014;109(6):449. doi: 10.1007/s00395-014-0449-2. Epub 2014 Oct 25. PubMed PMID: 25344085.
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12.416
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Zarak-Crnkovic M, Kania G, Jazwa-Kusior A, Czepiel M, Wijnen WJ, Czyz J, Muller-Edenborn B, Vdovenko D, Lindner D, Gil-Cruz C, Bachmann M, Westermann D, Ludewig B, Distler O, Luscher TF, Klingel K, Eriksson U, Blyszczuk P. Heart non-specific effector CD4+ T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis. Basic Res Cardiol. 2019 Dec 20;115(1):6. doi: 10.1007/s00395-019-0766-6. PubMed PMID: 31863205; PubMed Central PMCID: PMC6925074.
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12.416
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Gruhle S, Sauter M, Szalay G, Ettischer N, Kandolf R, Klingel K. The prostacyclin agonist iloprost aggravates fibrosis and enhances viral replication in enteroviral myocarditis by modulation of ERK signaling and increase of iNOS expression. Basic Res Cardiol. 2012 Sep;107(5):287. doi: 10.1007/s00395-012-0287-z. Epub 2012 Jul 27. PubMed PMID: 22836587.
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12.416
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Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschope C, Cooper LT Jr, Camici PG. Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document. Circ Heart Fail. 2020 Nov;13(11):e007405. doi: 10.1161/CIRCHEARTFAILURE.120.007405. Epub 2020 Nov 12. PubMed PMID: 33176455; PubMed Central PMCID: PMC7673642.
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10.447
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Besler C, Lang D, Urban D, Rommel KP, von Roeder M, Fengler K, Blazek S, Kandolf R, Klingel K, Thiele H, Linke A, Schuler G, Adams V, Lurz P. Plasma and Cardiac Galectin-3 in Patients With Heart Failure Reflects Both Inflammation and Fibrosis: Implications for Its Use as a Biomarker. Circ Heart Fail. 2017 Mar;10(3):e003804. doi: 10.1161/CIRCHEARTFAILURE.116.003804. PubMed PMID: 28288987.
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10.447
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Renault MA, Robbesyn F, Reant P, Douin V, Daret D, Allieres C, Belloc I, Couffinhal T, Arnal JF, Klingel K, Desgranges C, Dos Santos P, Charpentier F, Gadeau AP. Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy. Circ Heart Fail. 2010 May;3(3):431-9. doi: 10.1161/CIRCHEARTFAILURE.109.898114. Epub 2010 Mar 3. PubMed PMID: 20200330.
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10.447
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Pinkert S, Dieringer B, Klopfleisch R, Savvatis K, Van Linthout S, Pryshliak M, Tschope C, Klingel K, Kurreck J, Beling A, Fechner H. Early Treatment of Coxsackievirus B3-Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy. Circ Heart Fail. 2019 Nov;12(11):e005250. doi: 10.1161/CIRCHEARTFAILURE.119.005250. Epub 2019 Nov 13. PubMed PMID: 31718319.
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10.447
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Hou X, Chen G, Bracamonte-Baran W, Choi HS, Diny NL, Sung J, Hughes D, Won T, Wood MK, Talor MV, Hackam DJ, Klingel K, Davogustto G, Taegtmeyer H, Coppens I, Barin JG, Cihakova D. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019 Jul 2;28(1):172-189.e7. doi: 10.1016/j.celrep.2019.06.007. PubMed PMID: 31269438; PubMed Central PMCID: PMC6813836.
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9.995
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Klingel K, Fabritius C, Sauter M, Goldner K, Stauch D, Kandolf R, Ettischer N, Gahlen S, Schonberger T, Ebner S, Makrigiannis AP, Belanger S, Diefenbach A, Polic B, Pratschke J, Kotsch K. The activating receptor NKG2D of natural killer cells promotes resistance against enterovirus-mediated inflammatory cardiomyopathy. J Pathol. 2014 Oct;234(2):164-77. doi: 10.1002/path.4369. Epub 2014 Aug 6. PubMed PMID: 24797160.
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9.883
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Cavigelli-Brunner A, Schweiger M, Knirsch W, Stiasny B, Klingel K, Kretschmar O, Hubler M. VAD as bridge to recovery in anthracycline-induced cardiomyopathy and HHV6 myocarditis. Pediatrics. 2014 Sep;134(3):e894-9. doi: 10.1542/peds.2013-2272. Epub 2014 Aug 4. PubMed PMID: 25092940.
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9.703
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Kontorovich AR, Patel N, Moscati A, Richter F, Peter I, Purevjav E, Selejan SR, Kindermann I, Towbin JA, Bohm M, Klingel K, Gelb BD. Myopathic Cardiac Genotypes Increase Risk for Myocarditis. JACC Basic Transl Sci. 2021 Jul 26;6(7):584-592. doi: 10.1016/j.jacbts.2021.06.001. eCollection 2021 Jul. PubMed PMID: 34368507; PubMed Central PMCID: PMC8326270.
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9.531
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Peischard S, Moller M, Disse P, Ho HT, Verkerk AO, Strutz-Seebohm N, Budde T, Meuth SG, Schweizer PA, Morris S, Mucher L, Eisner V, Thomas D, Klingel K, Busch K, Seebohm G. Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Cell Mol Life Sci. 2022 Jul 21;79(8):440. doi: 10.1007/s00018-022-04435-7. PubMed PMID: 35864219; PubMed Central PMCID: PMC9304080.
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9.207
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Lurz P, Eitel I, Klieme B, Luecke C, de Waha S, Desch S, Fuernau G, Klingel K, Kandolf R, Grothoff M, Schuler G, Gutberlet M, Thiele H. The potential additional diagnostic value of assessing for pericardial effusion on cardiac magnetic resonance imaging in patients with suspected myocarditis. Eur Heart J Cardiovasc Imaging. 2014 Jun;15(6):643-50. doi: 10.1093/ehjci/jet267. Epub 2013 Dec 29. PubMed PMID: 24378485.
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9.13
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Meyer IS, Goetzke CC, Kespohl M, Sauter M, Heuser A, Eckstein V, Vornlocher HP, Anderson DG, Haas J, Meder B, Katus HA, Klingel K, Beling A, Leuschner F. Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. Front Immunol. 2018 Oct 8;9:2303. doi: 10.3389/fimmu.2018.02303. eCollection 2018. PubMed PMID: 30349538; PubMed Central PMCID: PMC6186826.
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8.786
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Weckbach LT, Curta A, Bieber S, Kraechan A, Brado J, Hellmuth JC, Muenchhoff M, Scherer C, Schroeder I, Irlbeck M, Maurus S, Ricke J, Klingel K, Kaab S, Orban M, Massberg S, Hausleiter J, Grabmaier U. Myocardial Inflammation and Dysfunction in COVID-19-Associated Myocardial Injury. Circ Cardiovasc Imaging. 2021 Jan;14(1):e012220. doi: 10.1161/CIRCIMAGING.120.011713. Epub 2021 Jan 19. PubMed PMID: 33463366.
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8.589
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Neumaier HL, Harel S, Klingel K, Kaya Z, Heuser A, Kespohl M, Beling A. ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage. Cells. 2020 Apr 28;9(5):1093. doi: 10.3390/cells9051093. PubMed PMID: 32354159; PubMed Central PMCID: PMC7290815.
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7.666
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Seidel F, Holtgrewe M, Al-Wakeel-Marquard N, Opgen-Rhein B, Dartsch J, Herbst C, Beule D, Pickardt T, Klingel K, Messroghli D, Berger F, Schubert S, Kuhnisch J, Klaassen S. Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis. Circ Genom Precis Med. 2021 Aug;14(4):e003250. doi: 10.1161/CIRCGEN.120.003250. Epub 2021 Jul 2. PubMed PMID: 34213952; PubMed Central PMCID: PMC8373449.
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7.465
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Opitz E, Koch A, Klingel K, Schmidt F, Prokop S, Rahnefeld A, Sauter M, Heppner FL, Volker U, Kandolf R, Kuckelkorn U, Stangl K, Kruger E, Kloetzel PM, Voigt A. Impairment of immunoproteasome function by beta5i/LMP7 subunit deficiency results in severe enterovirus myocarditis. PLoS Pathog. 2011 Sep;7(9):e1002233. doi: 10.1371/journal.ppat.1002233. Epub 2011 Sep 1. PubMed PMID: 21909276; PubMed Central PMCID: PMC3164653.
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7.464
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Imazio M, Klingel K, Kindermann I, Brucato A, De Rosa FG, Adler Y, De Ferrari GM. COVID-19 pandemic and troponin: indirect myocardial injury, myocardial inflammation or myocarditis? Heart. 2020 Aug;106(15):1127-1131. doi: 10.1136/heartjnl-2020-317186. Epub 2020 Jun 4. PubMed PMID: 32499236.
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7.365
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Latus H, Gummel K, Klingel K, Moysich A, Khalil M, Mazhari N, Bauer J, Kandolf R, Schranz D, Apitz C. Focal myocardial fibrosis assessed by late gadolinium enhancement cardiovascular magnetic resonance in children and adolescents with dilated cardiomyopathy. J Cardiovasc Magn Reson. 2015 May 15;17(1):34. doi: 10.1186/s12968-015-0142-0. PubMed PMID: 25976093; PubMed Central PMCID: PMC4432888.
|
6.903
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Schumm J, Greulich S, Wagner A, Grun S, Ong P, Bentz K, Klingel K, Kandolf R, Bruder O, Schneider S, Sechtem U, Mahrholdt H. Cardiovascular magnetic resonance risk stratification in patients with clinically suspected myocarditis. J Cardiovasc Magn Reson. 2014 Jan 26;16(1):14. doi: 10.1186/1532-429X-16-14. PubMed PMID: 24461053; PubMed Central PMCID: PMC3913958.
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6.903
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Paeschke A, Possehl A, Klingel K, Voss M, Voss K, Kespohl M, Sauter M, Overkleeft HS, Althof N, Garlanda C, Voigt A. The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3. Eur J Immunol. 2016 Mar;46(3):619-33. doi: 10.1002/eji.201545892. Epub 2015 Dec 28. PubMed PMID: 26578407.
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6.688
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Diny NL, Hou X, Barin JG, Chen G, Talor MV, Schaub J, Russell SD, Klingel K, Rose NR, Cihakova D. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. Eur J Immunol. 2016 Dec;46(12):2749-2760. doi: 10.1002/eji.201646557. Epub 2016 Oct 25. PubMed PMID: 27621211; PubMed Central PMCID: PMC5404278.
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6.688
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|
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Bigalke B, Klingel K, May AE, Kandolf R, Gawaz MG. Human herpesvirus 6 subtype A-associated myocarditis with 'apical ballooning'. Can J Cardiol. 2007 Apr;23(5):393-5. doi: 10.1016/s0828-282x(07)70775-4. PubMed PMID: 17440647; PubMed Central PMCID: PMC2649192.
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6.614
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Seferovic PM, Tsutsui H, Mcnamara DM, Ristic AD, Basso C, Bozkurt B, Cooper LT, Filippatos G, Ide T, Inomata T, Klingel K, Linhart A, Lyon AR, Mehra MR, Polovina M, Milinkovic I, Nakamura K, Anker SD, Veljic I, Ohtani T, Okumura T, Thum T, Tschope C, Rosano G, Coats AJS, Starling RC. Heart Failure Association, Heart Failure Society of America, and Japanese Heart Failure Society Position Statement on Endomyocardial Biopsy. J Card Fail. 2021 Jul;27(7):727-743. doi: 10.1016/j.cardfail.2021.04.010. Epub 2021 May 19. PubMed PMID: 34022400.
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6.592
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Sauter A, Ernemann U, Beck R, Klingel K, Mahrholdt H, Bitzer M, Horger M. Spectrum of imaging findings in immunocompromised patients with HHV-6 infection. AJR Am J Roentgenol. 2009 Nov;193(5):W373-80. doi: 10.2214/AJR.09.2687. PubMed PMID: 19843714.
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6.582
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Weinzierl AO, Szalay G, Wolburg H, Sauter M, Rammensee HG, Kandolf R, Stevanovic S, Klingel K. Effective chemokine secretion by dendritic cells and expansion of cross-presenting CD4-/CD8+ dendritic cells define a protective phenotype in the mouse model of coxsackievirus myocarditis. J Virol. 2008 Aug;82(16):8149-60. doi: 10.1128/JVI.00047-08. Epub 2008 Jun 11. PubMed PMID: 18550677; PubMed Central PMCID: PMC2519575.
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6.549
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Freiberg F, Sauter M, Pinkert S, Govindarajan T, Kaldrack J, Thakkar M, Fechner H, Klingel K, Gotthardt M. Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor. J Virol. 2014 Jul;88(13):7345-56. doi: 10.1128/JVI.00104-14. Epub 2014 Apr 16. PubMed PMID: 24741103; PubMed Central PMCID: PMC4054445.
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6.549
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Klingel K, Kandolf R. Osteopontin: a biomarker to predict the outcome of inflammatory heart disease. Semin Thromb Hemost. 2010 Mar;36(2):195-202. doi: 10.1055/s-0030-1251504. Epub 2010 Apr 22. PubMed PMID: 20414835.
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6.398
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Bauml M, Udi J, Klingel K, Bode C, Warnatz K, Zirlik A, Duerschmied D, Biever P. Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count. Clin Res Cardiol. 2019 Aug;108(8):963-966. doi: 10.1007/s00392-019-01434-w. Epub 2019 Feb 12. No abstract available. PubMed PMID: 30756153.
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6.138
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Bietenbeck M, Florian A, Shomanova Z, Klingel K, Yilmaz A. Novel CMR techniques enable detection of even mild autoimmune myocarditis in a patient with systemic lupus erythematosus. Clin Res Cardiol. 2017 Jul;106(7):560-563. doi: 10.1007/s00392-017-1100-7. Epub 2017 Mar 20. No abstract available. PubMed PMID: 28321496.
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6.138
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Muller II, Klingel K, Nikolaev VO, Jahns R, Gawaz MP, Weig HJ. Immunoadsorption in a 40 year old man with dilated cardiomyopathy and underlying active myocarditis. Clin Res Cardiol. 2008 Oct;97(10):787-90. doi: 10.1007/s00392-008-0689-y. Epub 2008 Jul 16. No abstract available. PubMed PMID: 18633566.
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6.138
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Wolf-Puetz A, Wein M, Niehues R, Horlitz M, Kelm M, Klingel K, Kandolf R, Klein RM. Multiple old myocardial scars and new onset of myocarditis in two young patients presenting with ventricular tachycardias and dilated cardiomyopathy. Clin Res Cardiol. 2011 Mar;100(3):253-60. doi: 10.1007/s00392-010-0250-7. Epub 2010 Dec 3. No abstract available. PubMed PMID: 21128079.
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6.138
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Ehrlich P, Klingel K, Ohlmann-Knafo S, Huttinger S, Sood N, Pickuth D, Kindermann M. Biopsy-proven lymphocytic myocarditis following first mRNA COVID-19 vaccination in a 40-year-old male: case report. Clin Res Cardiol. 2021 Nov;110(11):1855-1859. doi: 10.1007/s00392-021-01936-6. Epub 2021 Sep 6. No abstract available. PubMed PMID: 34487236; PubMed Central PMCID: PMC8419377.
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6.138
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Greulich S, Kindermann I, Schumm J, Perne A, Birkmeier S, Grun S, Ong P, Schaufele T, Klingel K, Schneider S, Kandolf R, Bohm M, Sechtem U, Mahrholdt H. Predictors of outcome in patients with parvovirus B19 positive endomyocardial biopsy. Clin Res Cardiol. 2016 Jan;105(1):37-52. doi: 10.1007/s00392-015-0884-6. Epub 2015 Jul 2. PubMed PMID: 26133158.
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6.138
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Zuern CS, Walker B, Sauter M, Schaub M, Chatterjee M, Mueller K, Rath D, Vogel S, Tegtmeyer R, Seizer P, Geisler T, Kandolf R, Lang F, Klingel K, Gawaz M, Borst O. Endomyocardial expression of SDF-1 predicts mortality in patients with suspected myocarditis. Clin Res Cardiol. 2015 Dec;104(12):1033-43. doi: 10.1007/s00392-015-0871-y. Epub 2015 May 26. PubMed PMID: 26008895.
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6.138
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Poller W, Haas J, Klingel K, Kuhnisch J, Gast M, Kaya Z, Escher F, Kayvanpour E, Degener F, Opgen-Rhein B, Berger F, Mochmann HC, Skurk C, Heidecker B, Schultheiss HP, Monserrat L, Meder B, Landmesser U, Klaassen S. Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene. J Am Heart Assoc. 2020 May 18;9(10):e015289. doi: 10.1161/JAHA.119.015289. Epub 2020 May 15. PubMed PMID: 32410525; PubMed Central PMCID: PMC7660888.
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6.106
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Greulich S, Seitz A, Muller KAL, Grun S, Ong P, Ebadi N, Kreisselmeier KP, Seizer P, Bekeredjian R, Zwadlo C, Grani C, Klingel K, Gawaz M, Sechtem U, Mahrholdt H. Predictors of Mortality in Patients With Biopsy-Proven Viral Myocarditis: 10-Year Outcome Data. J Am Heart Assoc. 2020 Aug 18;9(16):e015351. doi: 10.1161/JAHA.119.015351. Epub 2020 Aug 13. PubMed PMID: 32787653; PubMed Central PMCID: PMC7660832.
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6.106
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Tanacli R, Doeblin P, Gotze C, Zieschang V, Faragli A, Stehning C, Korosoglou G, Erley J, Weiss J, Berger A, Propper F, Steinbeis F, Kuhne T, Seidel F, Geisel D, Cannon Walter-Rittel T, Stawowy P, Witzenrath M, Klingel K, Van Linthout S, Pieske B, Tschope C, Kelle S. COVID-19 vs. Classical Myocarditis Associated Myocardial Injury Evaluated by Cardiac Magnetic Resonance and Endomyocardial Biopsy. Front Cardiovasc Med. 2021 Dec 24;8:737257. doi: 10.3389/fcvm.2021.737257. eCollection 2021. PubMed PMID: 35004872; PubMed Central PMCID: PMC8739473.
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5.846
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Fiegle DJ, Schober M, Dittrich S, Cesnjevar R, Klingel K, Volk T, Alkassar M, Seidel T. Severe T-System Remodeling in Pediatric Viral Myocarditis. Front Cardiovasc Med. 2021 Jan 18;7:624776. doi: 10.3389/fcvm.2020.624776. eCollection 2020. PubMed PMID: 33537349; PubMed Central PMCID: PMC7848076.
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5.846
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Tschope C, Alogna A, Faragli A, Klingel K, Schmidt G, Heilmann TW, B Bastos M, Spillmann F. Case Report First-in-Man Method Description: Left Ventricular Unloading With iVAC2L During Veno-Arterial Extracorporeal Membrane Oxygenation: From Veno-Arterial Extracorporeal Membrane Oxygenation to ECMELLA to EC-iVAC(R). Front Cardiovasc Med. 2020 Sep 25;7:563448. doi: 10.3389/fcvm.2020.563448. eCollection 2020. PubMed PMID: 33102536; PubMed Central PMCID: PMC7545402.
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5.846
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Bemtgen X, Klingel K, Hufnagel M, Janda A, Bode C, Staudacher DL, Supady A, Jandova I. Case Report: Lymphohistiocytic Myocarditis With Severe Cardiogenic Shock Requiring Mechanical Cardiocirculatory Support in Multisystem Inflammatory Syndrome Following SARS-CoV-2 Infection. Front Cardiovasc Med. 2021 Sep 9;8:716198. doi: 10.3389/fcvm.2021.716198. eCollection 2021. PubMed PMID: 34568458; PubMed Central PMCID: PMC8459926.
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5.846
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|
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Pappritz K, Savvatis K, Miteva K, Kerim B, Dong F, Fechner H, Muller I, Brandt C, Lopez B, Gonzalez A, Ravassa S, Klingel K, Diez J, Reinke P, Volk HD, Van Linthout S, Tschope C. Immunomodulation by adoptive regulatory T-cell transfer improves Coxsackievirus B3-induced myocarditis. FASEB J. 2018 Jun 4:fj201701408R. doi: 10.1096/fj.201701408R. Online ahead of print. PubMed PMID: 29863913.
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5.834
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Steinke K, Sachse F, Ettischer N, Strutz-Seebohm N, Henrion U, Rohrbeck M, Klosowski R, Wolters D, Brunner S, Franz WM, Pott L, Munoz C, Kandolf R, Schulze-Bahr E, Lang F, Klingel K, Seebohm G. Coxsackievirus B3 modulates cardiac ion channels. FASEB J. 2013 Oct;27(10):4108-21. doi: 10.1096/fj.13-230193. Epub 2013 Jun 27. PubMed PMID: 23825229.
|
5.834
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|
|
|
Elsanhoury A, Kuhl U, Stautner B, Klein O, Krannich A, Morris D, Willner M, Jankowska E, Klingel K, Van Linthout S, Tschope C. The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention. Viruses. 2022 Jan 31;14(2):299. doi: 10.3390/v14020299. PubMed PMID: 35215893; PubMed Central PMCID: PMC8879301.
|
5.818
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Pinkert S, Kespohl M, Kelm N, Kaya Z, Heuser A, Klingel K, Beling A. Exploration of Analgesia with Tramadol in the Coxsackievirus B3 Myocarditis Mouse Model. Viruses. 2021 Jun 24;13(7):1222. doi: 10.3390/v13071222. PubMed PMID: 34202636; PubMed Central PMCID: PMC8310306.
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5.818
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Kraft L, Sauter M, Seebohm G, Klingel K. In Vitro Model Systems of Coxsackievirus B3-Induced Myocarditis: Comparison of Commonly Used Cell Lines and Characterization of CVB3-Infected iCell(R) Cardiomyocytes. Viruses. 2021 Sep 14;13(9):1835. doi: 10.3390/v13091835. PubMed PMID: 34578416; PubMed Central PMCID: PMC8472939.
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5.818
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Muller I, Janson L, Sauter M, Pappritz K, Linthout SV, Tschope C, Klingel K. Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis. Viruses. 2021 May 12;13(5):889. doi: 10.3390/v13050889. PubMed PMID: 34065891; PubMed Central PMCID: PMC8151145.
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5.818
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|
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Hazini A, Dieringer B, Klingel K, Pryshliak M, Geisler A, Kobelt D, Daberkow O, Kurreck J, Linthout SV, Fechner H. Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H. Viruses. 2021 Sep 24;13(10):1918. doi: 10.3390/v13101918. PubMed PMID: 34696348; PubMed Central PMCID: PMC8539752.
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5.818
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|
|
|
Favere K, Bosman M, Klingel K, Heymans S, Van Linthout S, Delputte PL, De Sutter J, Heidbuchel H, Guns PJ. Toll-Like Receptors: Are They Taking a Toll on the Heart in Viral Myocarditis? Viruses. 2021 May 27;13(6):1003. doi: 10.3390/v13061003. PubMed PMID: 34072044; PubMed Central PMCID: PMC8227433.
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5.818
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|
|
|
Ho HT, Peischard S, Strutz-Seebohm N, Klingel K, Seebohm G. Myocardial Damage by SARS-CoV-2: Emerging Mechanisms and Therapies. Viruses. 2021 Sep 21;13(9):1880. doi: 10.3390/v13091880. PubMed PMID: 34578462; PubMed Central PMCID: PMC8473126.
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5.818
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|
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Szalay G, Sauter M, Hald J, Weinzierl A, Kandolf R, Klingel K. Sustained nitric oxide synthesis contributes to immunopathology in ongoing myocarditis attributable to interleukin-10 disorders. Am J Pathol. 2006 Dec;169(6):2085-93. doi: 10.2353/ajpath.2006.060350. PubMed PMID: 17148671; PubMed Central PMCID: PMC1762471.
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5.77
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Jakel S, Kuckelkorn U, Szalay G, Plotz M, Textoris-Taube K, Opitz E, Klingel K, Stevanovic S, Kandolf R, Kotsch K, Stangl K, Kloetzel PM, Voigt A. Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis. Am J Pathol. 2009 Aug;175(2):510-8. doi: 10.2353/ajpath.2009.090033. Epub 2009 Jul 9. PubMed PMID: 19590042; PubMed Central PMCID: PMC2716952.
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5.77
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Szalay G, Meiners S, Voigt A, Lauber J, Spieth C, Speer N, Sauter M, Kuckelkorn U, Zell A, Klingel K, Stangl K, Kandolf R. Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes. Am J Pathol. 2006 May;168(5):1542-52. doi: 10.2353/ajpath.2006.050865. PubMed PMID: 16651621; PubMed Central PMCID: PMC1606581.
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5.77
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Klingel K, Schnorr JJ, Sauter M, Szalay G, Kandolf R. beta2-microglobulin-associated regulation of interferon-gamma and virus-specific immunoglobulin G confer resistance against the development of chronic coxsackievirus myocarditis. Am J Pathol. 2003 May;162(5):1709-20. doi: 10.1016/s0002-9440(10)64305-2. PubMed PMID: 12707055; PubMed Central PMCID: PMC1851178.
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5.77
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Seizer P, Klingel K, Sauter M, Westermann D, Ochmann C, Schonberger T, Schleicher R, Stellos K, Schmidt EM, Borst O, Bigalke B, Kandolf R, Langer H, Gawaz M, May AE. Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis. J Mol Cell Cardiol. 2012 Jul;53(1):6-14. doi: 10.1016/j.yjmcc.2012.03.004. Epub 2012 Mar 15. PubMed PMID: 22446162.
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5.763
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Lang C, Sauter M, Szalay G, Racchi G, Grassi G, Rainaldi G, Mercatanti A, Lang F, Kandolf R, Klingel K. Connective tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis. J Mol Med (Berl). 2008 Jan;86(1):49-60. doi: 10.1007/s00109-007-0249-3. Epub 2007 Sep 11. PubMed PMID: 17846733.
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5.606
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Ebermann L, Wika S, Klumpe I, Hammer E, Klingel K, Lassner D, Volker U, Erben U, Zeichhardt H, Schultheiss HP, Dorner A. The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis. Lab Invest. 2012 Jan;92(1):125-34. doi: 10.1038/labinvest.2011.145. Epub 2011 Oct 3. PubMed PMID: 21968812.
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5.502
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Hammer E, Phong TQ, Steil L, Klingel K, Salazar MG, Bernhardt J, Kandolf R, Kroemer HK, Felix SB, Volker U. Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: analysis of changes in the myocardial proteome. Proteomics. 2010 May;10(9):1802-18. doi: 10.1002/pmic.200900734. PubMed PMID: 20213679.
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5.393
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|
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Nishtala K, Phong TQ, Steil L, Sauter M, Salazar MG, Kandolf R, Kroemer HK, Felix SB, Volker U, Klingel K, Hammer E. Virus-induced dilated cardiomyopathy is characterized by increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes. Proteomics. 2011 Nov;11(22):4310-20. doi: 10.1002/pmic.201100229. Epub 2011 Sep 22. PubMed PMID: 21954127.
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5.393
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Li J, Leschka S, Rutschow S, Schwimmbeck PL, Husmann L, Noutsias M, Westermann D, Poller W, Zeichhardt H, Klingel K, Tschope C, Schultheiss HP, Pauschinger M. Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis. Eur J Pharmacol. 2007 Jan 5;554(1):60-8. doi: 10.1016/j.ejphar.2006.08.024. Epub 2006 Aug 26. PubMed PMID: 17113076.
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5.195
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Weinzierl AO, Rudolf D, Maurer D, Wernet D, Rammensee HG, Stevanovic S, Klingel K. Identification of HLA-A*01- and HLA-A*02-restricted CD8+ T-cell epitopes shared among group B enteroviruses. J Gen Virol. 2008 Sep;89(Pt 9):2090-2097. doi: 10.1099/vir.0.2008/000711-0. PubMed PMID: 18753217.
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5.141
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Maier A, Braig M, Jakob K, Bienert T, Schaper M, Merkle A, Wadle C, Menza M, Neudorfer I, Bojti I, Stachon P, Duerschmied D, Hilgendorf I, Heidt T, Bode C, Peter K, Klingel K, von Elverfeldt D, von Zur Muhlen C. Molecular magnetic resonance imaging of activated platelets allows noninvasive detection of early myocarditis in mice. Sci Rep. 2020 Aug 6;10(1):13211. doi: 10.1038/s41598-020-70043-9. PubMed PMID: 32764735; PubMed Central PMCID: PMC7413393.
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4.996
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Brendel JM, Klingel K, Kubler J, Muller KAL, Hagen F, Gawaz M, Nikolaou K, Greulich S, Krumm P. Comprehensive Cardiac Magnetic Resonance to Detect Subacute Myocarditis. J Clin Med. 2022 Aug 30;11(17):5113. doi: 10.3390/jcm11175113. PubMed PMID: 36079039; PubMed Central PMCID: PMC9457022.
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4.964
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Krumm P, Brendel JM, Klingel K, Muller KAL, Kubler J, Grani C, Gawaz M, Nikolaou K, Greulich S. Using Multiparametric Cardiac Magnetic Resonance to Phenotype and Differentiate Biopsy-Proven Chronic from Healed Myocarditis and Dilated Cardiomyopathy. J Clin Med. 2022 Aug 28;11(17):5047. doi: 10.3390/jcm11175047. PubMed PMID: 36078976; PubMed Central PMCID: PMC9457265.
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4.964
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Hazini A, Pryshliak M, Bruckner V, Klingel K, Sauter M, Pinkert S, Kurreck J, Fechner H. Heparan Sulfate Binding Coxsackievirus B3 Strain PD: A Novel Avirulent Oncolytic Agent Against Human Colorectal Carcinoma. Hum Gene Ther. 2018 Nov;29(11):1301-1314. doi: 10.1089/hum.2018.036. Epub 2018 Jun 20. PubMed PMID: 29739251.
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4.793
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Pankuweit S, Klingel K. Viral myocarditis: from experimental models to molecular diagnosis in patients. Heart Fail Rev. 2013 Nov;18(6):683-702. doi: 10.1007/s10741-012-9357-4. PubMed PMID: 23070541.
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4.654
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Yilmaz A, Ferreira V, Klingel K, Kandolf R, Neubauer S, Sechtem U. Role of cardiovascular magnetic resonance imaging (CMR) in the diagnosis of acute and chronic myocarditis. Heart Fail Rev. 2013 Nov;18(6):747-60. doi: 10.1007/s10741-012-9356-5. PubMed PMID: 23076423.
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4.654
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Callegari A, Quandt D, Schmitz A, Klingel K, Balmer C, Dave H, Kretschmar O, Knirsch W. Findings and Outcome of Transcatheter Right Ventricular Endomyocardial Biopsy and Hemodynamic Assessment in Children with Suspected Myocarditis or Cardiomyopathy. Int J Environ Res Public Health. 2022 Aug 21;19(16):10406. doi: 10.3390/ijerph191610406. PubMed PMID: 36012045; PubMed Central PMCID: PMC9408529.
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4.614
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Ettischer-Schmid N, Normann A, Sauter M, Kraft L, Kalbacher H, Kandolf R, Flehmig B, Klingel K. A new monoclonal antibody (Cox mAB 31A2) detects VP1 protein of coxsackievirus B3 with high sensitivity and specificity. Virchows Arch. 2016 Nov;469(5):553-562. doi: 10.1007/s00428-016-2008-8. Epub 2016 Aug 27. PubMed PMID: 27566306.
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4.535
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Lindner D, Li J, Savvatis K, Klingel K, Blankenberg S, Tschope C, Westermann D. Cardiac fibroblasts aggravate viral myocarditis: cell specific coxsackievirus B3 replication. Mediators Inflamm. 2014;2014:519528. doi: 10.1155/2014/519528. Epub 2014 Oct 13. PubMed PMID: 25374444; PubMed Central PMCID: PMC4211177.
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4.529
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Becher PM, Gotzhein F, Klingel K, Escher F, Blankenberg S, Westermann D, Lindner D. Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis. J Immunol Res. 2017;2017:6590609. doi: 10.1155/2017/6590609. Epub 2017 Mar 2. PubMed PMID: 28352641; PubMed Central PMCID: PMC5352897.
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4.493
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Seidel F, Laser KT, Klingel K, Dartsch J, Theisen S, Pickardt T, Holtgrewe M, Gartner A, Berger F, Beule D, Milting H, Schubert S, Klaassen S, Kuhnisch J. Pathogenic Variants in Cardiomyopathy Disorder Genes Underlie Pediatric Myocarditis-Further Impact of Heterozygous Immune Disorder Gene Variants? J Cardiovasc Dev Dis. 2022 Jul 5;9(7):216. doi: 10.3390/jcdd9070216. PubMed PMID: 35877578; PubMed Central PMCID: PMC9321514.
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4.415
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Goerlich N, Klingel K, Stangl K, Gaedeke J, Eckardt KU, Kettritz R. NEPHRO-ZEBRA-acute troponin increase in a kidney transplant recipient-the unknown knowns? J Nephrol. 2021 Jun;34(3):931-933. doi: 10.1007/s40620-021-00990-7. Epub 2021 Mar 24. No abstract available. PubMed PMID: 33761121; PubMed Central PMCID: PMC8192373.
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4.393
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Callegari A, Klingel K, Kelly-Geyer J, Berger C, Geiger J, Knirsch W. Difficulties in diagnosis of SARS-CoV-2 myocarditis in an adolescent. Swiss Med Wkly. 2022 Jul 28;152:w30214. doi: 10.4414/smw.2022.w30214. eCollection 2022 Jul 18. PubMed PMID: 35964255.
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4.203
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Klingel K, Sauter M, Bock CT, Szalay G, Schnorr JJ, Kandolf R. Molecular pathology of inflammatory cardiomyopathy. Med Microbiol Immunol. 2004 May;193(2-3):101-7. doi: 10.1007/s00430-003-0190-1. Epub 2003 Aug 14. PubMed PMID: 12920583.
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4.148
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Selinka HC, Wolde A, Sauter M, Kandolf R, Klingel K. Virus-receptor interactions of coxsackie B viruses and their putative influence on cardiotropism. Med Microbiol Immunol. 2004 May;193(2-3):127-31. doi: 10.1007/s00430-003-0193-y. Epub 2003 Aug 14. PubMed PMID: 12920584.
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4.148
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Tschope C, Nelki V, Trippel TD, Klingel K, Abawi D, Alogna A. Safety and usefulness of left ventricular endomyocardial biopsy in new- onset acute heart failure requiring mechanical support by an Impella(R) device. Int J Cardiol. 2022 Dec 1;368:49-52. doi: 10.1016/j.ijcard.2022.08.010. Epub 2022 Aug 6. PubMed PMID: 35944774.
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4.039
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Seitz A, Martinez Pereyra V, Hubert A, Klingel K, Bekeredjian R, Sechtem U, Ong P. Epicardial and microvascular coronary artery spasm in biopsy-proven viral myocarditis. Int J Cardiol. 2022 Aug 1;360:1-4. doi: 10.1016/j.ijcard.2022.05.008. Epub 2022 May 6. PubMed PMID: 35533750.
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4.039
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Seidel F, Opgen-Rhein B, Rentzsch A, Boehne M, Wannenmacher B, Boecker D, Reineker K, Grafmann M, Wiegand G, Hecht T, Kiski D, Fischer M, Papakostas K, Ruf B, Kramp J, Khalil M, Kaestner M, Steinmetz M, Fischer G, Ozcan S, Freudenthal N, Schweigmann U, Hellwig R, Pickardt T, Klingel K, Messroghli D, Schubert S; MYKKE consortium. Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE". Int J Cardiol. 2022 Jun 15;357:95-104. doi: 10.1016/j.ijcard.2022.03.026. Epub 2022 Mar 15. PubMed PMID: 35304189.
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4.039
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Deluigi CC, Ong P, Hill S, Wagner A, Kispert E, Klingel K, Kandolf R, Sechtem U, Mahrholdt H. ECG findings in comparison to cardiovascular MR imaging in viral myocarditis. Int J Cardiol. 2013 Apr 30;165(1):100-6. doi: 10.1016/j.ijcard.2011.07.090. Epub 2011 Sep 1. PubMed PMID: 21885134.
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4.039
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Grabmaier U, Brenner C, Methe H, Kaczmarek I, Schramm R, Klingel K, Hagl C, Franz WM. An alternative immunosuppressive regimen to prolong transplant free survival in a patient with giant cell myocarditis. Int J Cardiol. 2013 Sep 20;168(1):e27-8. doi: 10.1016/j.ijcard.2013.05.078. Epub 2013 Jun 2. No abstract available. PubMed PMID: 23735345.
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4.039
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Stiermaier T, Fohrenbach F, Klingel K, Kandolf R, Boudriot E, Sandri M, Linke A, Rommel KP, Desch S, Schuler G, Thiele H, Lurz P. Biventricular endomyocardial biopsy in patients with suspected myocarditis: Feasibility, complication rate and additional diagnostic value. Int J Cardiol. 2017 Mar 1;230:364-370. doi: 10.1016/j.ijcard.2016.12.103. Epub 2016 Dec 21. PubMed PMID: 28040278.
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4.039
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Veronese G, Ammirati E, Chen C, Klingel K, Suzuki M, Okumura T, Maisch B, Zuo H, Ni L, Jiang J, Zhang J, Wang H, Zhou N, Tschope C, Cooper LT, Wang DW. Management perspectives from the 2019 Wuhan international workshop on fulminant myocarditis. Int J Cardiol. 2021 Feb 1;324:131-138. doi: 10.1016/j.ijcard.2020.10.063. Epub 2020 Oct 26. PubMed PMID: 33122017.
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4.039
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Pavlicek V, Kindermann I, Wintrich J, Mahfoud F, Klingel K, Bohm M, Ukena C. Ventricular arrhythmias and myocardial inflammation: Long-term follow-up of patients with suspected myocarditis. Int J Cardiol. 2019 Jan 1;274:132-137. doi: 10.1016/j.ijcard.2018.07.142. Epub 2018 Aug 9. PubMed PMID: 30122502.
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4.039
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Degener F, Salameh A, Manuylova T, Pickardt T, Kostelka M, Daehnert I, Berger F, Messroghli D, Schubert S, Klingel K. First paediatric cohort for the evaluation of inflammation in endomyocardial biopsies derived from congenital heart surgery. Int J Cardiol. 2020 Mar 15;303:36-40. doi: 10.1016/j.ijcard.2019.10.006. Epub 2019 Oct 5. PubMed PMID: 31611088.
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4.039
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Borst O, Schaub M, Walker B, Sauter M, Muenzer P, Gramlich M, Mueller K, Geisler T, Lang F, Klingel K, Kandolf R, Bigalke B, Gawaz M, Zuern CS. CXCL16 is a novel diagnostic marker and predictor of mortality in inflammatory cardiomyopathy and heart failure. Int J Cardiol. 2014 Oct 20;176(3):896-903. doi: 10.1016/j.ijcard.2014.08.033. Epub 2014 Aug 13. PubMed PMID: 25223819.
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4.039
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Seizer P, Klingel K, Stickel J, Dorn C, Horger M, Kandolf R, Bigalke B, May AE, Gawaz M, Schreieck J. Left ventricular site-directed biopsy guided by left ventricular voltage mapping: a proof of principle. Int J Cardiol. 2013 Oct 3;168(3):3113-4. doi: 10.1016/j.ijcard.2013.04.068. Epub 2013 Apr 28. No abstract available. PubMed PMID: 23632116.
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4.039
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Heinzmann D, Schibilsky D, Gramlich M, Klingel K, Kandolf R, Rosenberger P, Gawaz M, Schreieck J, Schlensak C, Seizer P. Ablation of an electrical storm in a patient with giant cell myocarditis using continuous flow left ventricular assist device and percutaneous right ventricular assist device. Int J Cardiol. 2016 Apr 15;209:84-6. doi: 10.1016/j.ijcard.2016.02.060. Epub 2016 Feb 3. No abstract available. PubMed PMID: 26882191.
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4.039
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Fishbein GA, Leone O, Basso C, Fallon JT, Klingel K, Tan C. Commentary on why implementing and standardizing histologic diagnosis of myocarditis is crucial for the clinical setting and patient care. Cardiovasc Pathol. 2022 Dec 30:107515. doi: 10.1016/j.carpath.2022.107515. Online ahead of print. PubMed PMID: 36592720.
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3.975
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Lu ZA, Aubry MC, Fallon JT, Fishbein MC, Giordano C, Klingel K, Leone O, Rizzo S, Veinot JP, Halushka MK. Myocarditis and endomyocardial biopsy: achieving consensus diagnosis on 100 cases. Cardiovasc Pathol. 2023 Jan-Feb;62:107492. doi: 10.1016/j.carpath.2022.107492. Epub 2022 Oct 28. PubMed PMID: 36404460.
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3.975
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Wessely R, Vorpahl M, Schomig A, Klingel K. Late constrictive involvement of the pericardium in a case of previous myocarditis. Cardiovasc Pathol. 2004 Nov-Dec;13(6):327-9. doi: 10.1016/j.carpath.2004.07.002. PubMed PMID: 15556780.
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3.975
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Ursu ON, Beyer T, Sauter M, Fragasso A, Bundschuh S, Klingel K, Munz B. TRAF6: A player in CVB3-induced myocarditis? Cytokine. 2019 Oct;122:154143. doi: 10.1016/j.cyto.2017.08.023. Epub 2017 Sep 6. PubMed PMID: 28886971.
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3.926
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|
Westphal DS, Krafft H, Biller R, Klingel K, Gaa J, Mueller CS, Martens E. Myocarditis or inherited disease? - The multifaceted presentation of arrhythmogenic cardiomyopathy. Gene. 2022 Jun 15;827:146470. doi: 10.1016/j.gene.2022.146470. Epub 2022 Apr 4. PubMed PMID: 35381313.
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3.913
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Ameling S, Bischof J, Dorr M, Konemann S, Empen K, Weitmann K, Klingel K, Beug D, Dhople VM, Volker U, Hammer E, Felix SB. Analysis of DCM associated protein alterations of human right and left ventricles. J Proteomics. 2021 Jan 16;231:104018. doi: 10.1016/j.jprot.2020.104018. Epub 2020 Oct 17. PubMed PMID: 33075551.
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3.855
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Helluy X, Sauter M, Ye YX, Lykowsky G, Kreutner J, Yilmaz A, Jahns R, Boivin V, Kandolf R, Jakob PM, Hiller KH, Klingel K. In vivo T2* weighted MRI visualizes cardiac lesions in murine models of acute and chronic viral myocarditis. PLoS One. 2017 Mar 6;12(3):e0172084. doi: 10.1371/journal.pone.0172084. eCollection 2017. PubMed PMID: 28264039; PubMed Central PMCID: PMC5338786.
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3.752
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Kaese S, Larbig R, Rohrbeck M, Frommeyer G, Dechering D, Olligs J, Schonhofer-Merl S, Wessely R, Klingel K, Seebohm G, Eckardt L. Electrophysiological alterations in a murine model of chronic coxsackievirus B3 myocarditis. PLoS One. 2017 Jun 23;12(6):e0180029. doi: 10.1371/journal.pone.0180029. eCollection 2017. PubMed PMID: 28644868; PubMed Central PMCID: PMC5482483.
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3.752
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Heinzmann D, Bangert A, Muller AM, von Ungern-Sternberg SN, Emschermann F, Schonberger T, Chatterjee M, Mack AF, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer HF, Katus H, Fischer G, May AE, Kaya Z, Seizer P. The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis. PLoS One. 2015 Apr 20;10(4):e0124606. doi: 10.1371/journal.pone.0124606. eCollection 2015. PubMed PMID: 25894208; PubMed Central PMCID: PMC4404136.
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3.752
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Becher PM, Hinrichs S, Fluschnik N, Hennigs JK, Klingel K, Blankenberg S, Westermann D, Lindner D. Role of Toll-like receptors and interferon regulatory factors in different experimental heart failure models of diverse etiology: IRF7 as novel cardiovascular stress-inducible factor. PLoS One. 2018 Mar 14;13(3):e0193844. doi: 10.1371/journal.pone.0193844. eCollection 2018. PubMed PMID: 29538462; PubMed Central PMCID: PMC5851607.
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3.752
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Bachelier K, Biehl S, Schwarz V, Kindermann I, Kandolf R, Sauter M, Ukena C, Yilmaz A, Sliwa K, Bock CT, Klingel K, Bohm M. Parvovirus B19-induced vascular damage in the heart is associated with elevated circulating endothelial microparticles. PLoS One. 2017 May 22;12(5):e0176311. doi: 10.1371/journal.pone.0176311. eCollection 2017. PubMed PMID: 28531186; PubMed Central PMCID: PMC5439674.
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3.752
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Respondek D, Voss M, Kuhlewindt I, Klingel K, Kruger E, Beling A. PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection. PLoS One. 2017 Mar 9;12(3):e0173259. doi: 10.1371/journal.pone.0173259. eCollection 2017. PubMed PMID: 28278207; PubMed Central PMCID: PMC5344377.
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3.752
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Savvatis K, van Linthout S, Miteva K, Pappritz K, Westermann D, Schefold JC, Fusch G, Weithauser A, Rauch U, Becher PM, Klingel K, Ringe J, Kurtz A, Schultheiss HP, Tschope C. Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis. PLoS One. 2012;7(7):e41047. doi: 10.1371/journal.pone.0041047. Epub 2012 Jul 17. PubMed PMID: 22815907; PubMed Central PMCID: PMC3398879.
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3.752
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Kiblboeck D, Klingel K, Genger M, Traxler S, Braunsteiner N, Steinwender C, Kellermair J. Myocarditis following mRNA COVID-19 vaccination: call for endomyocardial biopsy. ESC Heart Fail. 2022 Jun;9(3):1996-2002. doi: 10.1002/ehf2.13791. Epub 2022 Feb 23. PubMed PMID: 35194974; PubMed Central PMCID: PMC9065833.
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3.612
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Mueller KAL, Patzelt J, Sauter M, Maier P, Gekeler S, Klingel K, Kandolf R, Seizer P, Gawaz M, Geisler T, Langer HF. Myocardial expression of the anaphylatoxin receptor C3aR is associated with cardiac inflammation and prognosis in patients with non-ischaemic heart failure. ESC Heart Fail. 2018 Oct;5(5):846-857. doi: 10.1002/ehf2.12298. Epub 2018 Aug 31. PubMed PMID: 30168657; PubMed Central PMCID: PMC6165948.
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3.612
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Blaschke F, Lacour P, Dang PL, Parwani AS, Hohendanner F, Walter T, Klingel K, Kuhl U, Heinzel FR, Sherif M, Boldt LH, Pieske B, Tschope C. Wearable cardioverter-defibrillator: friend or foe in suspected myocarditis? ESC Heart Fail. 2021 Aug;8(4):2591-2596. doi: 10.1002/ehf2.13340. Epub 2021 May 1. PubMed PMID: 33932118; PubMed Central PMCID: PMC8318471.
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3.612
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Seidel F, Scheibenbogen C, Heidecke H, Opgen-Rhein B, Pickardt T, Klingel K, Berger F, Messroghli D, Schubert S. Compensatory Upregulation of Anti-Beta-Adrenergic Receptor Antibody Levels Might Prevent Heart Failure Presentation in Pediatric Myocarditis. Front Pediatr. 2022 Apr 28;10:881208. doi: 10.3389/fped.2022.881208. eCollection 2022. PubMed PMID: 35573966; PubMed Central PMCID: PMC9096696.
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3.569
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Bultmann BD, Klingel K, Sotlar K, Bock CT, Baba HA, Sauter M, Kandolf R. Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease. Hum Pathol. 2003 Jan;34(1):92-5. doi: 10.1053/hupa.2003.48. PubMed PMID: 12605372.
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3.526
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Plonka J, Gawda R, Sacha J, Bugajski J, Brzostowicz T, Molsa M, Czarnik T, Klingel K, Gierlotka M. Fulminant myocarditis and acute heart failure in the light of new American Heart Association 2020 guidelines. Mechanical cardiac support and endomyocardial biopsy. What should be first? Cardiol J. 2022;29(4):714-717. doi: 10.5603/CJ.a2022.0052. Epub 2022 Jun 28. No abstract available. PubMed PMID: 35762076; PubMed Central PMCID: PMC9273245.
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3.487
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Ong P, Athansiadis A, Hill S, Kispert EM, Borgulya G, Klingel K, Kandolf R, Sechtem U, Mahrholdt H. Usefulness of pericardial effusion as new diagnostic criterion for noninvasive detection of myocarditis. Am J Cardiol. 2011 Aug 1;108(3):445-52. doi: 10.1016/j.amjcard.2011.03.068. Epub 2011 May 31. PubMed PMID: 21624548.
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3.133
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Jacoby C, Borg N, Heusch P, Sauter M, Bonner F, Kandolf R, Klingel K, Schrader J, Flogel U. Visualization of immune cell infiltration in experimental viral myocarditis by (19)F MRI in vivo. MAGMA. 2014 Feb;27(1):101-6. doi: 10.1007/s10334-013-0391-6. Epub 2013 Jul 4. PubMed PMID: 23824166.
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2.533
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Veronese G, Cipriani M, Petrella D, Pedrotti P, Giannattasio C, Garascia A, Oliva F, Klingel K, Frigerio M, Ammirati E. Not every fulminant lymphocytic myocarditis fully recovers. J Cardiovasc Med (Hagerstown). 2018 Aug;19(8):453-454. doi: 10.2459/JCM.0000000000000664. No abstract available. PubMed PMID: 29889166.
|
2.43
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Bohne M, Bohnen S, Voigt HC, van der Schalk H, Chung DU, Willems S, Klingel K, Kivelitz D, Bahlmann E. Systemic thrombo-embolic events in a middle-aged male with Loeffler endocarditis without peripheral eosinophilia-a case report. BMC Cardiovasc Disord. 2022 Dec 12;22(1):541. doi: 10.1186/s12872-022-02911-3. PubMed PMID: 36510139; PubMed Central PMCID: PMC9742649.
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2.174
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|
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Bohne M, Chung DU, Tigges E, van der Schalk H, Waddell D, Schenker N, Willems S, Klingel K, Kivelitz D, Bahlmann E. Short-term use of "ECMELLA" in the context of fulminant eosinophilic myocarditis with cardiogenic shock. BMC Cardiovasc Disord. 2020 Dec 10;20(1):519. doi: 10.1186/s12872-020-01808-3. PubMed PMID: 33302874; PubMed Central PMCID: PMC7731477.
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2.174
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Greulich S, Klingel K. COVID-19 and Myocarditis: Findings from Cardiac Magnetic Resonance Imaging and Endomyocardial Biopsies. Hamostaseologie. 2021 Oct;41(5):366-370. doi: 10.1055/a-1539-8664. Epub 2021 Aug 14. PubMed PMID: 34391209.
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2.145
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Lindner D, Hilbrandt M, Marggraf K, Becher PM, Hilfiker-Kleiner D, Klingel K, Pauschinger M, Schultheiss HP, Tschope C, Westermann D. Protective Function of STAT3 in CVB3-Induced Myocarditis. Cardiol Res Pract. 2012;2012:437623. doi: 10.1155/2012/437623. Epub 2012 May 24. PubMed PMID: 22675647; PubMed Central PMCID: PMC3366200.
|
1.99
|
|
|
|
Augustin N, Schreiber C, Klingel K, Kandolf R, Lange R. [Rare case of enterovirus myocarditis with consecutive acute heart failure and subsequent "rescue therapy" with biventricular assist device]. Herz. 2003 Aug;28(5):457-60. doi: 10.1007/s00059-003-2440-9. German. PubMed PMID: 12928746.
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1.74
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Schubert S, Opgen-Rhein B, Boehne M, Weigelt A, Wagner R, Muller G, Rentzsch A, Zu Knyphausen E, Fischer M, Papakostas K, Wiegand G, Ruf B, Hannes T, Reineker K, Kiski D, Khalil M, Steinmetz M, Fischer G, Pickardt T, Klingel K, Messroghli DR, Degener F; MYKKE consortium. Severe heart failure and the need for mechanical circulatory support and heart transplantation in pediatric patients with myocarditis: Results from the prospective multicenter registry "MYKKE". Pediatr Transplant. 2019 Nov;23(7):e13548. doi: 10.1111/petr.13548. Epub 2019 Jul 11. PubMed PMID: 31297930.
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1.551
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|
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Schroeter MR, Klingel K, Korsten P, Hasenfuss G. Fulminant Lyme myocarditis without any other signs of Lyme disease in a 37-year-old male patient with microscopic polyangiitis-a case report. Eur Heart J Case Rep. 2022 Feb 9;6(3):ytac062. doi: 10.1093/ehjcr/ytac062. eCollection 2022 Mar. PubMed PMID: 35291336; PubMed Central PMCID: PMC8916016.
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Popa MA, Klingel K, Hadamitzky M, Deisenhofer I, Hessling G. An unusual case of severe myocarditis in a genetic cardiomyopathy: a case report. Eur Heart J Case Rep. 2020 Jun 9;4(4):1-7. doi: 10.1093/ehjcr/ytaa124. eCollection 2020 Aug. PubMed PMID: 32974466; PubMed Central PMCID: PMC7501922.
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Chatzantonis G, Evers G, Meier C, Bietenbeck M, Florian A, Klingel K, Bleckmann A, Yilmaz A. Immune Checkpoint Inhibitor-Associated Myocarditis: A Run of Bad Luck or Rather Deficient-Monitoring Protocol? JACC Case Rep. 2020 Apr 15;2(4):630-635. doi: 10.1016/j.jaccas.2019.12.047. eCollection 2020 Apr. PubMed PMID: 34317309; PubMed Central PMCID: PMC8298681.
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Kindermann M, Sood N, Ehrlich P, Klingel K. Fast spontaneous recovery from acute necrotizing eosinophilic myopericarditis without need for immunosuppressive therapy: a case report of a 27-year-old male. Eur Heart J Case Rep. 2020 Jun 17;4(4):1-5. doi: 10.1093/ehjcr/ytaa153. eCollection 2020 Aug. PubMed PMID: 32974437; PubMed Central PMCID: PMC7501893.
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Racchi G, Klingel K, Kandolf R, Grassi G. Targeting of protease 2A genome by single and multiple siRNAs as a strategy to impair CVB3 life cycle in permissive HeLa cells. Methods Find Exp Clin Pharmacol. 2009 Mar;31(2):63-70. doi: 10.1358/mf.2009.31.2.1354129. PubMed PMID: 19455260.
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Ursu ON, Sauter M, Ettischer N, Kandolf R, Klingel K. Heme oxygenase-1 mediates oxidative stress and apoptosis in coxsackievirus B3-induced myocarditis. Cell Physiol Biochem. 2014;33(1):52-66. doi: 10.1159/000356649. Epub 2014 Jan 2. PubMed PMID: 24401606.
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Bock CT, Duchting A, Utta F, Brunner E, Sy BT, Klingel K, Lang F, Gawaz M, Felix SB, Kandolf R. Molecular phenotypes of human parvovirus B19 in patients with myocarditis. World J Cardiol. 2014 Apr 26;6(4):183-95. doi: 10.4330/wjc.v6.i4.183. PubMed PMID: 24772258; PubMed Central PMCID: PMC3999338.
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